C₁₂H₁₂ClFO₂

Base Information

Chemical Name:C₁₂H₁₂ClFO₂
CAS No.:1040860-60-3
Molecular Formula:C₁₂H₁₂ClFO₂
Molecular Weight:242.677
Hs Code.:

C<sub>12</sub>H<sub>12</sub>ClFO<sub>2</sub>

Synonyms:C₁₂H₁₂ClFO₂

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Chemical Property of C₁₂H₁₂ClFO₂

Chemical Property:

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Technology Process of C₁₂H₁₂ClFO₂

There total 5 articles about C₁₂H₁₂ClFO₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 473706-11-5
4-(4-fluorophenyl)-tetrahydro-2H-pyran-4-carboxylic acid

: 1040860-60-3
C₁₂H₁₂ClFO₂

Guidance literature:: With thionyl chloride; for 2h; Heating / reflux;

Reference yield:

: 587-88-2
ethyl 2-(4-fluorophenyl)acetate

: 1040860-60-3
C₁₂H₁₂ClFO₂

Guidance literature:: Multi-step reaction with 3 steps

1: sodium hydride / 1-methyl-pyrrolidin-2-one; diethyl ether / 5 h / 20 °C

2: potassium hydroxide; ethanol; water / 4 h / Heating / reflux

3: thionyl chloride / 2 h / Heating / reflux

With potassium hydroxide; thionyl chloride; ethanol; water; sodium hydride; In 1-methyl-pyrrolidin-2-one; diethyl ether;

Reference yield:

: 405-50-5
p-Fluorophenylacetic acid

: 1040860-60-3
C₁₂H₁₂ClFO₂

Guidance literature:: Multi-step reaction with 5 steps

1: thionyl chloride / 2 h / Heating / reflux

2: triethylamine / dichloromethane / 2 h / 0 °C

3: sodium hydride / 1-methyl-pyrrolidin-2-one; diethyl ether / 5 h / 20 °C

4: potassium hydroxide; ethanol; water / 4 h / Heating / reflux

5: thionyl chloride / 2 h / Heating / reflux

With potassium hydroxide; thionyl chloride; ethanol; water; sodium hydride; triethylamine; In 1-methyl-pyrrolidin-2-one; diethyl ether; dichloromethane;