Dalamid

Base Information

Chemical Name:Dalamid
CAS No.:61090-95-7
Molecular Formula:C28H38 N6 O6 S
Molecular Weight:586.712
Hs Code.:
NSC Number:351913
DSSTox Substance ID:DTXSID50976589
Mol file:61090-95-7.mol

Synonyms:2-Ala-Met-enkephalinamide;Ala(2)-Met(5)-enkephalinamide;D-Ala(2)-Leu(5)-enkephalinamide;D-Ala(2)-Met(5)-enkephalinamide;D-ala(2)-methionine-enkephalinamide;D-enkephalin;DALA;DALAMID;dalamide;DAME;enkephalinamide, Ala(2), Met(5);enkephalinamide-Met, Ala(2)-;enkephalinamide-Met, alanine(2)-;Met-enkephalinamide, Ala(2)-;methionine-enkephalinamide, Ala(2)-

Suppliers and Price of Dalamid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
D-ALA2-MET-ENKEPHALINAMIDE 95.00%
25MG
$ 1000.52

Total 24 raw suppliers

Chemical Property of Dalamid

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Boiling Point:1057.4 °C at 760 mmHg
Flash Point:593.3 °C
PSA：231.04000
Density:1.286 g/cm³
LogP:2.29780
Storage Temp.:-15°C
XLogP3:-0.1
Hydrogen Bond Donor Count:7
Hydrogen Bond Acceptor Count:8
Rotatable Bond Count:16
Exact Mass:586.25735413
Heavy Atom Count:41
Complexity:878

Purity/Quality:

99%, ^*data from raw suppliers

D-ALA2-MET-ENKEPHALINAMIDE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C(=O)NCC(=O)NC(CC1=CC=CC=C1)C(=O)NC(CCSC)C(=O)N)NC(=O)C(CC2=CC=C(C=C2)O)N

Technology Process of Dalamid

There total 9 articles about Dalamid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 66960-03-0
Boc Tyr D_.Ala Gly Phe Met NH₂

: 61090-95-7
(S)-2-[(S)-2-(2-{(R)-2-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-propionylamino}-acetylamino)-3-phenyl-propionylamino]-4-methylsulfanyl-butyramide

Guidance literature:: With hydrogenchloride; acetic acid; In various solvent(s); for 1.5h;

Reference yield:

: 71591-34-9
N-(tert-butyloxycarbonyl)-L-tyrosyl-D-alanine

: 61090-95-7
(S)-2-[(S)-2-(2-{(R)-2-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-propionylamino}-acetylamino)-3-phenyl-propionylamino]-4-methylsulfanyl-butyramide

Guidance literature:: Multi-step reaction with 7 steps

1: N-hydroxybenzotriazole, triethylamine, dicyclohexylcarbodiimide / formamide / 10 h. 0 deg C, 10 h. room temp.

2: H₂O, NaOH / methanol

3: N-hydroxybenzotriazole, triethylamine, dicyclohexylcarbodiimide / dimethylformamide

4: H₂O, NaOH / methanol

5: N-hydroxybenzotriazole, triethylamine, dicyclohexylcarbodiimide / dimethylformamide

6: NH₃ / methanol

7: HCl, acetic acid / various solvent(s) / 1.5 h

With hydrogenchloride; sodium hydroxide; ammonia; water; benzotriazol-1-ol; acetic acid; triethylamine; dicyclohexyl-carbodiimide; In methanol; formamide; N,N-dimethyl-formamide;

Reference yield:

: 64410-47-5,79225-08-4
N-(tert-butyloxycarbonyl)-L-tyrosyl-D-alanylglycine

: 61090-95-7
(S)-2-[(S)-2-(2-{(R)-2-[(S)-2-Amino-3-(4-hydroxy-phenyl)-propionylamino]-propionylamino}-acetylamino)-3-phenyl-propionylamino]-4-methylsulfanyl-butyramide

Guidance literature:: Multi-step reaction with 5 steps

1: N-hydroxybenzotriazole, triethylamine, dicyclohexylcarbodiimide / dimethylformamide

2: H₂O, NaOH / methanol

3: N-hydroxybenzotriazole, triethylamine, dicyclohexylcarbodiimide / dimethylformamide

4: NH₃ / methanol

5: HCl, acetic acid / various solvent(s) / 1.5 h

With hydrogenchloride; sodium hydroxide; ammonia; water; benzotriazol-1-ol; acetic acid; triethylamine; dicyclohexyl-carbodiimide; In methanol; N,N-dimethyl-formamide;