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L-Methionine

Base Information Edit
  • Chemical Name:L-Methionine
  • CAS No.:63-68-3
  • Molecular Formula:C5H11NO2S
  • Molecular Weight:149.214
  • Hs Code.:29304010
  • Mol file:63-68-3.mol
L-Methionine

Synonyms:2-Amino-4-methylthiobutanoic acid (S)-;L-Methionine,;Methionine, L-;2-Amino-4-(methylthio)butyric acid, (S)-;L-Homocysteine, S-methyl-;L-Methionin;L-alpha-Amino-gamma-methylthiobutyric acid;(2S)-2-amino-4-(methylsulfanyl)butanoic acid;L-Methionine (AJI92;USP24);Methionine, L- (8CI);L-Methioninum;Methionine (VAN);(L)-Methionine;(S)-methionine;L-2-Amino-4methylthiobutyric acid;S-Methyl-L-homocysteine;(S)-2-amino-4-(methylthio)butyric acid;Methioninum [INN-Latin];2-Amino-4-methylthiobutanoic acid;Acimethin;

Suppliers and Price of L-Methionine
Supply Marketing:Edit
Business phase:
The product has achieved commercial mass production*data from LookChem market partment
Manufacturers and distributors:
  • Manufacture/Brand
  • Chemicals and raw materials
  • Packaging
  • price
  • Usbiological
  • L-Methionine
  • 10g
  • $ 36.00
  • TRC
  • L-Methionine
  • 10mg
  • $ 55.00
  • TCI Chemical
  • L-Methionine >99.0%(T)
  • 500g
  • $ 150.00
  • TCI Chemical
  • L-Methionine >99.0%(T)
  • 25g
  • $ 20.00
  • TCI Chemical
  • L-Methionine >99.0%(T)
  • 100g
  • $ 48.00
  • Sigma-Aldrich
  • L-Methionine from non-animal source, meets EP, JP, USP testing specifications, suitable for cell culture, 99.0-101.0%
  • 25g
  • $ 33.20
  • Sigma-Aldrich
  • L-Methionine reagent grade, ≥98% (HPLC)
  • 25g
  • $ 24.20
  • Sigma-Aldrich
  • L-Methionine BioUltra, ≥99.5% (NT)
  • 25g-f
  • $ 45.20
  • Sigma-Aldrich
  • L-Methionine for synthesis
  • 25 g
  • $ 37.09
  • Sigma-Aldrich
  • L-Methionine BioUltra, ≥99.5% (NT)
  • 25 g
  • $ 46.80
Total 346 raw suppliers
Chemical Property of L-Methionine Edit
Chemical Property:
  • Appearance/Colour:White crystalline powder 
  • Melting Point:284 °C (dec.)(lit.) 
  • Refractive Index:1.5216 (estimate) 
  • Boiling Point:306.9 °C at 760 mmHg 
  • PKA:2.13(at 25℃) 
  • Flash Point:139.4 °C 
  • PSA:88.62000 
  • Density:1.206 g/cm3 
  • LogP:0.85170 
  • Storage Temp.:Store at RT. 
  • Solubility.:1 M HCl: 0.5 M at 20 °C, clear, colorless 
  • Water Solubility.:Soluble 
  • XLogP3:-1.2
  • Hydrogen Bond Donor Count:1
  • Hydrogen Bond Acceptor Count:3
  • Rotatable Bond Count:3
  • Exact Mass:149.05104977
  • Heavy Atom Count:9
  • Complexity:91.4
Purity/Quality:

99%, *data from raw suppliers

L-Methionine *data from reagent suppliers

Safty Information:
  • Pictogram(s):  
  • Hazard Codes: 
  • Statements: 33 
  • Safety Statements: 24/25 
MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:
  • Canonical SMILES:CSCCC(C(=O)[O-])[NH3+]
  • Isomeric SMILES:CSCC[C@@H](C(=O)[O-])[NH3+]
  • Description L-methionine is a sulfur-containing essential L-amino acid that is important in many body functions. Methionine is a dietary indispensable amino acid required for normal growth and development of humans, other mammals, and avian species. In addition to being a substrate for protein synthesis, it is an intermediate in transmethylation reactions, serving as the major methyl group donor.It must be obtained from diet and food sources since it is unable to be biosynthesized in the body. The minimum daily requirement of L-methionine for an adult male is 13 milligrams per kilogram of body weight. This quantity is normally easy to obtain from a complete diet. Methionine is accepted as the metabolic precursor for cysteine. Only the sulfur atom from methionine is transferred to cysteine; the carbon skeleton of cysteine is donated by serine. (PMID: 16702340).It helps the body produce SAMe (S-Adenosyl-L-methionine), which has been used to treat psychiatric illnesses, infertility, liver problems, premenstrual disorders, and musculoskeletal conditions. Studies on SAMe have shown that it is as effective as tricyclic antidepressants in alleviating depression. Ongoing studies that show promise are also being conducted to determine how effective L-Methionine may be for treating HIV/AIDS, liver damage, Parkinson's disease, and urinary tract infections. Colorless or white lustrous plates, or a white crystalline powder. It has a slight, characteristic odor. It is soluble in water, in alkali solutions, and in dilute mineral acids. It is slightly soluble in alcohol and practically insoluble in ether.
  • Uses Amino acid drugs, nutritional supplements. Used for fatty liver and cirrhosis. Also widely used as feed additives to improve feed quality, improve the utilization of the native protein and promote animal growth. Such as DL-methionine can increase egg production of chickens, pigs make weight gain, more milk cows and so on. Adverse reaction: hepatic coma hanged. Nutritional supplements. One of the essential amino acids of the human body. Because the price is higher than DL-methionine and the results are equal, so commonly used DL-methionine. For biochemical studies and nutritional supplements, and as adjunctive treatment for pneumonia, liver cirrhosis and fatty liver. Essential aminoacid for human development. Hepatoprotectant; antidote (acetominophen poisoning); urinary acidifier. methionine is slows down and normalizes oil gland sebum production. Methionine is also used as a texturizer in cosmetic creams. It is an essential amino acid found in a number of proteins and obtained by means of fermentation. L-Methionine is used as an essential amino acid for human development and therapeutically acts as an antidote for acetaminophen poisoning. It serves as a chelating agent for heavy metals, as a flavoring agent and nutritional supplement for foods. It acts as a feed additive, vegetable oil enrichment and as a single cell protein. In addition to this, it is used as a hepatoprotectant and also acts as a lipotropic agent and prevents excess fat buildup in the liver.
  • Therapeutic Function Lipotropic
Technology Process of L-Methionine

There total 150 articles about L-Methionine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:
Guidance literature:
With water; at 170 ℃; for 0.05h; Microwave irradiation;
DOI:10.1016/j.tetlet.2008.09.027
Guidance literature:
With tetrabutyl ammonium fluoride; In tetrahydrofuran; water; at 20 ℃; for 1h;
DOI:10.1002/ejoc.201700063
Guidance literature:
In water; at 37 ℃; for 10h; NADH, ammonium chloride, sodium formate, D-amino acid oxidase, catalase, leucine dehydrogenase, formate dehydrogenase, Tris-HCl buffer, pH 8.5;
DOI:10.1039/c39900000947
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