1-(2,6-Dimethylphenyl)piperazine

Base Information

Chemical Name:1-(2,6-Dimethylphenyl)piperazine
CAS No.:1012-91-5
Molecular Formula:C12H18N2
Molecular Weight:190.288
Hs Code.:2933599090
European Community (EC) Number:213-791-4
UNII:6FD6M9XAW2
DSSTox Substance ID:DTXSID70143776
Nikkaji Number:J217.131G
Wikidata:Q83007774
Mol file:1012-91-5.mol

Synonyms:1-(2,6-dimethylphenyl)piperazine;1012-91-5;1-(2,6-Xylyl)piperazine;Piperazine, 1-(2,6-dimethylphenyl)-;Piperazine, 1-(2,6-xylyl)-;EINECS 213-791-4;Piperazine,1-(2,6-dimethylphenyl)-;1-(2,6-dimethyl-phenyl)-piperazine;6FD6M9XAW2;SCHEMBL336283;DTXSID70143776;4-(2,6-Dimethylphenyl) piperazine;GS1417;MFCD00038009;AKOS003884887;1-(2,6-xylyl)piperazine, AldrichCPR;FS-1658;FT-0629093;EN300-80344

Suppliers and Price of 1-(2,6-Dimethylphenyl)piperazine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
1-(2,6-Dimethylphenyl)piperazine
100mg
$ 75.00

Matrix Scientific
1-(2,6-Dimethylphenyl)piperazine 97%
1g
$ 60.00

Atlantic Research Chemicals
1-(2,6-Dimethylphenyl)piperazine 95%
250mgs:
$ 14.14

American Custom Chemicals Corporation
1-(2,6-DIMETHYLPHENYL)PIPERAZINE 95.00%
5G
$ 870.75

Alichem
1-(2,6-Dimethylphenyl)piperazine
10g
$ 361.92

Alichem
1-(2,6-Dimethylphenyl)piperazine
5g
$ 255.20

AK Scientific
1-(2,6-Dimethylphenyl)piperazine
1g
$ 76.00

AHH
1-(2,6-Dimethylphenyl)piperazine 97%
250g
$ 346.00

Total 23 raw suppliers

Chemical Property of 1-(2,6-Dimethylphenyl)piperazine

Chemical Property:

Appearance/Colour:Gray power
Vapor Pressure:0.000451mmHg at 25°C
Refractive Index:1.537
Boiling Point:315 °C at 760 mmHg
PKA:8.96±0.10(Predicted)
Flash Point:138.3 °C
PSA：15.27000
Density:0.999 g/cm³
LogP:2.10680
XLogP3:2.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:190.146998583
Heavy Atom Count:14
Complexity:165

Purity/Quality:

99%, ^*data from raw suppliers

1-(2,6-Dimethylphenyl)piperazine ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi
Statements: 36/37/38-36
Safety Statements: 26-36/37/39

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=C(C(=CC=C1)C)N2CCNCC2

Technology Process of 1-(2,6-Dimethylphenyl)piperazine

There total 4 articles about 1-(2,6-Dimethylphenyl)piperazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 1012-92-6
1-(2,6-dimethylphenyl)piperazine hydrochloride

: 1012-91-5
1-(2,6-dimethylphenyl)-piperazine

Guidance literature:: With sodium hydroxide; In water; at 20 ℃; for 0.5h; pH=11 - 12;
DOI:10.1111/cbdd.13324

Reference yield: 62.0%

: 110-85-0
piperazine

: 6781-98-2
2,6-dimethyl-1-chlorobenzene

: 1012-91-5
1-(2,6-dimethylphenyl)-piperazine

Guidance literature:: With tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; 2-dicyclohexylphosphino-2′,6′-di-i-propoxy-1,1′-biphenyl; sodium t-butanolate; In 1,4-dioxane; at 100 ℃; for 0.166667h; Temperature;
DOI:10.1021/acs.orglett.6b02591

Reference yield: 45.0%

: 110-85-0
piperazine

: 576-22-7
2-Bromo-m-xylene

: 1012-91-5
1-(2,6-dimethylphenyl)-piperazine

Guidance literature:: With tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; 2,2'-bis-(diphenylphosphino)-1,1'-binaphthyl; sodium t-butanolate; In toluene; at 100 ℃; for 24h; Inert atmosphere;
DOI:10.1016/j.ejmech.2021.113841