2-butynoic acid [3-(2-bromo-4,5-dimethoxyphenyl)propyl]-(4-methoxybenzyl)amide

Base Information

Chemical Name:2-butynoic acid [3-(2-bromo-4,5-dimethoxyphenyl)propyl]-(4-methoxybenzyl)amide
CAS No.:947530-71-4
Molecular Formula:C₂₃H₂₆BrNO₄
Molecular Weight:460.368
Hs Code.:

Synonyms:2-butynoic acid [3-(2-bromo-4,5-dimethoxyphenyl)propyl]-(4-methoxybenzyl)amide

Suppliers and Price of 2-butynoic acid [3-(2-bromo-4,5-dimethoxyphenyl)propyl]-(4-methoxybenzyl)amide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 2-butynoic acid [3-(2-bromo-4,5-dimethoxyphenyl)propyl]-(4-methoxybenzyl)amide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 2-butynoic acid [3-(2-bromo-4,5-dimethoxyphenyl)propyl]-(4-methoxybenzyl)amide

There total 4 articles about 2-butynoic acid [3-(2-bromo-4,5-dimethoxyphenyl)propyl]-(4-methoxybenzyl)amide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 3-(2-bromo-4,5-dimethoxyphenyl)-N-(4-methoxybenzyl)acrylamide

: 947530-71-4
2-butynoic acid [3-(2-bromo-4,5-dimethoxyphenyl)propyl]-(4-methoxybenzyl)amide

Guidance literature:: Multi-step reaction with 3 steps

1: 89 percent / TsNHNH₂; aq. AcONa / 1,2-dimethoxy-ethane / 2 h / Heating

2: 86 percent / BF₃*THF / tetrahydrofuran / Heating

3: 96 percent / dioxane / 20 °C

With boron trifluoride-tetrahydrofuran complex; sodium acetate; toluene-4-sulfonic acid hydrazide; In tetrahydrofuran; 1,4-dioxane; 1,2-dimethoxyethane;
DOI:10.1021/ol071079g

Reference yield:

: 947530-54-3
3-(2-bromo-4,5-dimethoxyphenyl)-N-(4-methoxybenzyl)propionamide

: 947530-71-4
2-butynoic acid [3-(2-bromo-4,5-dimethoxyphenyl)propyl]-(4-methoxybenzyl)amide

Guidance literature:: Multi-step reaction with 2 steps

1: 86 percent / BF₃*THF / tetrahydrofuran / Heating

2: 96 percent / dioxane / 20 °C

With boron trifluoride-tetrahydrofuran complex; In tetrahydrofuran; 1,4-dioxane;
DOI:10.1021/ol071079g

Reference yield:

: 151539-52-5
2-bromo-4,5-dimethoxycinnamic acid

: 947530-71-4
2-butynoic acid [3-(2-bromo-4,5-dimethoxyphenyl)propyl]-(4-methoxybenzyl)amide

Guidance literature:: Multi-step reaction with 4 steps

1: DMAP; DCC / CH₂Cl₂ / 20 °C

2: 89 percent / TsNHNH₂; aq. AcONa / 1,2-dimethoxy-ethane / 2 h / Heating

3: 86 percent / BF₃*THF / tetrahydrofuran / Heating

4: 96 percent / dioxane / 20 °C

With dmap; boron trifluoride-tetrahydrofuran complex; sodium acetate; toluene-4-sulfonic acid hydrazide; dicyclohexyl-carbodiimide; In tetrahydrofuran; 1,4-dioxane; 1,2-dimethoxyethane; dichloromethane;
DOI:10.1021/ol071079g