4β-[2-acetamido-4-methylthiazole-5-sulfonamido]podophyllotoxin

Base Information

• Chemical Name: 4β-[2-acetamido-4-methylthiazole-5-sulfonamido]podophyllotoxin
• CAS No.: 1365699-71-3
• Molecular Formula: C₂₈H₂₉N₃O₁₀S₂
• Molecular Weight: 631.684
• Mol file: 1365699-71-3.mol

Synonyms:4β-[2-acetamido-4-methylthiazole-5-sulfonamido]podophyllotoxin

Chemical Property of 4β-[2-acetamido-4-methylthiazole-5-sulfonamido]podophyllotoxin

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

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Technology Process of 4β-[2-acetamido-4-methylthiazole-5-sulfonamido]podophyllotoxin

There total 1 articles about 4β-[2-acetamido-4-methylthiazole-5-sulfonamido]podophyllotoxin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

2-acetamido-4-methyl-5-thiazolesulfonyl chloride (69812-29-9) + 4β-amino-4-deoxypodophyllotoxin (155252-35-0) → 4β-[2-acetamido-4-methylthiazole-5-sulfonamido]podophyllotoxin (1365699-71-3)

Guidance literature:

With triethylamine; In dichloromethane; at 20 ℃; for 3h;

DOI:10.1016/j.bmc.2012.01.039

upstream raw materials:

2-acetamido-4-methyl-5-thiazolesulfonyl chloride

4β-amino-4-deoxypodophyllotoxin