5-chloro-2'-fluoro-2-(5-hydroxymethyl-2-methyl-imidazol-1-yl)-benzophenone

Base Information

Chemical Name:5-chloro-2'-fluoro-2-(5-hydroxymethyl-2-methyl-imidazol-1-yl)-benzophenone
CAS No.:59468-72-3
Molecular Formula:C₁₈H₁₄ClFN₂O₂
Molecular Weight:344.773
Hs Code.:

Synonyms:5-chloro-2'-fluoro-2-(5-hydroxymethyl-2-methyl-imidazol-1-yl)-benzophenone

Suppliers and Price of 5-chloro-2'-fluoro-2-(5-hydroxymethyl-2-methyl-imidazol-1-yl)-benzophenone

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 5-chloro-2'-fluoro-2-(5-hydroxymethyl-2-methyl-imidazol-1-yl)-benzophenone

Chemical Property:

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Technology Process of 5-chloro-2'-fluoro-2-(5-hydroxymethyl-2-methyl-imidazol-1-yl)-benzophenone

There total 11 articles about 5-chloro-2'-fluoro-2-(5-hydroxymethyl-2-methyl-imidazol-1-yl)-benzophenone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 59468-73-4
5-aminomethyl-1-[4-chloro-2-(2-fluorobenzoyl)phenyl]-2-methyl-imidazole dihydrochloride

: 59468-72-3
5-chloro-2'-fluoro-2-(5-hydroxymethyl-2-methyl-imidazol-1-yl)-benzophenone

Guidance literature:: With sodium nitrite; In water;

Reference yield:

: 7-chloro-1,3-dihydro-5-(2-fluorophenyl)-2-(1-nitromethylene)-2H-1,4-benzodiazepine 4-oxide

: 59468-72-3
5-chloro-2'-fluoro-2-(5-hydroxymethyl-2-methyl-imidazol-1-yl)-benzophenone

Guidance literature:: Multi-step reaction with 6 steps

1: aluminum nickel / tetrahydrofuran; methanol

2: PPA; acetic anhydride / methanol; dichloromethane; water

3: hydrogen / dichloromethane; water; acetic acid; Petroleum ether

4: manganese dioxide / toluene

5: hydrogenchloride / water

6: sodium nitrite / water

With hydrogenchloride; PPA; manganese dioxide; hydrogen; acetic anhydride; sodium nitrite; aluminum nickel; In tetrahydrofuran; methanol; dichloromethane; water; acetic acid; toluene; Petroleum ether;

Reference yield:

: 59469-03-3
8-chloro-6-(2-fluorophenyl)-1-hydroxy-methyl-4H-imidazo(1,5-a)(1,4)-benzodiazepine

: 59468-72-3
5-chloro-2'-fluoro-2-(5-hydroxymethyl-2-methyl-imidazol-1-yl)-benzophenone

Guidance literature:: Multi-step reaction with 3 steps

1: pyridine; sodium methylate; acetic anhydride / methanol

2: hydrogenchloride / water

3: sodium nitrite / water

With pyridine; hydrogenchloride; sodium methylate; acetic anhydride; sodium nitrite; In methanol; water;