methyl cis-4-[1-(5-bromopyridin-2-yl)-1-hydroxyethyl]cyclohexane-carboxylate

Base Information

• Chemical Name: methyl cis-4-[1-(5-bromopyridin-2-yl)-1-hydroxyethyl]cyclohexane-carboxylate
• CAS No.: 1411772-58-1
• Molecular Formula: C₁₅H₂₀BrNO₃
• Molecular Weight: 342.233

Synonyms:methyl cis-4-[1-(5-bromopyridin-2-yl)-1-hydroxyethyl]cyclohexane-carboxylate

Chemical Property of methyl cis-4-[1-(5-bromopyridin-2-yl)-1-hydroxyethyl]cyclohexane-carboxylate

Chemical Property:

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Technology Process of methyl cis-4-[1-(5-bromopyridin-2-yl)-1-hydroxyethyl]cyclohexane-carboxylate

There total 1 articles about methyl cis-4-[1-(5-bromopyridin-2-yl)-1-hydroxyethyl]cyclohexane-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

methyl 4-[(5-bromopyridin-2-yl)carbonyl]cyclohexanecarboxylate + methylmagnesium bromide (75-16-1) → methyl trans-4-[1-(5-bromopyridin-2-yl)-1-hydroxyethyl]cyclohexanecarboxylate (1411772-44-5) + methyl cis-4-[1-(5-bromopyridin-2-yl)-1-hydroxyethyl]cyclohexane-carboxylate (1411772-58-1)

Guidance literature:

methyl 4-[(5-bromopyridin-2-yl)carbonyl]cyclohexanecarboxylate; methylmagnesium bromide; In tetrahydrofuran; diethyl ether; at -40 ℃; for 0.5h;

With ammonium chloride; In tetrahydrofuran; diethyl ether; water;

upstream raw materials:

methylmagnesium bromide

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