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Technology Process of N6-benzoyl-5'-O-(tert-butyldimethylsilyl)-2'-O-(4-methoxytetrahydropyran-4-yl)adenosine

N6-benzoyl-5'-O-(tert-butyldimethylsilyl)-2'-O-(4-methoxytetrahydropyran-4-yl)adenosine

Base Information
  • Chemical Name:N6-benzoyl-5'-O-(tert-butyldimethylsilyl)-2'-O-(4-methoxytetrahydropyran-4-yl)adenosine
  • CAS No.:80186-03-4
  • Molecular Formula:C29H41N5O7Si
  • Molecular Weight:599.759
  • Hs Code.:
N<sup>6</sup>-benzoyl-5'-O-(tert-butyldimethylsilyl)-2'-O-(4-methoxytetrahydropyran-4-yl)adenosine

Synonyms:N6-benzoyl-5'-O-(tert-butyldimethylsilyl)-2'-O-(4-methoxytetrahydropyran-4-yl)adenosine

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Chemical Property of N6-benzoyl-5'-O-(tert-butyldimethylsilyl)-2'-O-(4-methoxytetrahydropyran-4-yl)adenosine
Chemical Property:
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Technology Process of N6-benzoyl-5'-O-(tert-butyldimethylsilyl)-2'-O-(4-methoxytetrahydropyran-4-yl)adenosine

There total 1 articles about N6-benzoyl-5'-O-(tert-butyldimethylsilyl)-2'-O-(4-methoxytetrahydropyran-4-yl)adenosine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 62.0%

N<sup>6</sup>-benzoyl-2'-O-(tetrahydro-4-methoxy-2H-pyran-4-yl)adenosine
80185-98-4

N6-benzoyl-2'-O-(tetrahydro-4-methoxy-2H-pyran-4-yl)adenosine

tert-butyldimethylsilyl chloride
18162-48-6

tert-butyldimethylsilyl chloride

N<sup>6</sup>-benzoyl-5'-O-(tert-butyldimethylsilyl)-2'-O-(4-methoxytetrahydropyran-4-yl)adenosine
80186-03-4

N6-benzoyl-5'-O-(tert-butyldimethylsilyl)-2'-O-(4-methoxytetrahydropyran-4-yl)adenosine

Guidance literature:
With 1H-imidazole; In N,N-dimethyl-formamide; for 20h;
DOI:10.1021/jo00343a007
upstream raw materials:

N6-benzoyl-2'-O-(tetrahydro-4-methoxy-2H-pyran-4-yl)adenosine

tert-butyldimethylsilyl chloride

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