Tert-butyl 4-oxidanyl-2-(phenylmethoxycarbonylamino)butanoate

Base Information

Chemical Name:Tert-butyl 4-oxidanyl-2-(phenylmethoxycarbonylamino)butanoate
CAS No.:149967-08-8
Molecular Formula:C₁₆H₂₃NO₅
Molecular Weight:309.362
Hs Code.:
DSSTox Substance ID:DTXSID60550511

Synonyms:149967-08-8;N-Cbz-D-homoserine tert-butyl ester;tert-butyl 4-hydroxy-2-(phenylmethoxycarbonylamino)butanoate;tert-butyl 4-oxidanyl-2-(phenylmethoxycarbonylamino)butanoate;SCHEMBL995705;DTXSID60550511;tert-Butyl N-[(benzyloxy)carbonyl]homoserinate;A808988;4-hydroxy-2-(phenylmethoxycarbonylamino)butanoic acid tert-butyl ester

Suppliers and Price of Tert-butyl 4-oxidanyl-2-(phenylmethoxycarbonylamino)butanoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Acrotein
N-Cbz-D-homoserinetert-butylester 97%
1g
$ 550.00

Acrotein
N-Cbz-D-homoserinetert-butylester 97%
0.25g
$ 247.50

Total 2 raw suppliers

Chemical Property of Tert-butyl 4-oxidanyl-2-(phenylmethoxycarbonylamino)butanoate

Chemical Property:

XLogP3:2.1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:9
Exact Mass:309.15762283
Heavy Atom Count:22
Complexity:358

Purity/Quality:

97% ^*data from raw suppliers

N-Cbz-D-homoserinetert-butylester 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)OC(=O)C(CCO)NC(=O)OCC1=CC=CC=C1

Technology Process of Tert-butyl 4-oxidanyl-2-(phenylmethoxycarbonylamino)butanoate

There total 5 articles about Tert-butyl 4-oxidanyl-2-(phenylmethoxycarbonylamino)butanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: (R)-2-Benzyloxycarbonylamino-4-ethoxycarbonyloxy-4-oxo-butyric acid tert-butyl ester

: 149967-08-8
N-<(phenylmethoxy)carbonyl>-D-homoserine, 1,1-dimethylethyl ester

Guidance literature:: With sodium tetrahydroborate; In tetrahydrofuran; water; at 21 ℃; for 3h; Yield given;
DOI:10.1021/jm00031a018

Reference yield:

: 501-53-1,94274-21-2
benzyl chloroformate

: 149967-08-8
N-<(phenylmethoxy)carbonyl>-D-homoserine, 1,1-dimethylethyl ester

Guidance literature:: Multi-step reaction with 5 steps

1: Na₂CO₃ / dioxane; H₂O / 15 h / 23 °C

2: H₂SO₄ / CH₂Cl₂ / 15 h

3: 97 percent / 1N NaOH / methanol / 2 h / 21 °C

4: N-methylmorpholine / tetrahydrofuran / 0.25 h / -10 - 23 °C

5: NaBH₄ / tetrahydrofuran; H₂O / 3 h / 21 °C

With 4-methyl-morpholine; sodium hydroxide; sodium tetrahydroborate; sulfuric acid; sodium carbonate; In tetrahydrofuran; 1,4-dioxane; methanol; dichloromethane; water;
DOI:10.1021/jm00031a018

Reference yield:

: 28862-78-4
(+)-N-Cbz-β-methyl-D-aspartate

: 149967-08-8
N-<(phenylmethoxy)carbonyl>-D-homoserine, 1,1-dimethylethyl ester

Guidance literature:: Multi-step reaction with 4 steps

1: H₂SO₄ / CH₂Cl₂ / 15 h

2: 97 percent / 1N NaOH / methanol / 2 h / 21 °C

3: N-methylmorpholine / tetrahydrofuran / 0.25 h / -10 - 23 °C

4: NaBH₄ / tetrahydrofuran; H₂O / 3 h / 21 °C

With 4-methyl-morpholine; sodium hydroxide; sodium tetrahydroborate; sulfuric acid; In tetrahydrofuran; methanol; dichloromethane; water;
DOI:10.1021/jm00031a018