MH 031

Base Information

Chemical Name:MH 031
CAS No.:122246-01-9
Molecular Formula:C₇H₈O₄
Molecular Weight:156.138
Hs Code.:
Mol file:122246-01-9.mol

Synonyms:MH 031

Suppliers and Price of MH 031

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of MH 031

Chemical Property:

Vapor Pressure:6.58E-08mmHg at 25°C
Boiling Point:411.1°C at 760 mmHg
Flash Point:178.9°C
PSA：63.60000
Density:1.343g/cm³
LogP:0.33440

Purity/Quality:: 95% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of MH 031

There total 8 articles about MH 031 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 122246-00-8
3-(2-oxo-2,5-dihydrofuran-3-yl)propionic acid methyl ester

: 122246-01-9
MH 031

Guidance literature:: With water; lithium hydroxide; In tetrahydrofuran; at 20 ℃; for 3h; Inert atmosphere;
DOI:10.1016/j.tetlet.2013.07.087

Reference yield: 65.0%

: 201230-82-2
carbon monoxide

: 6-hydroxy-3-hexynoic acid

: 122246-01-9
MH 031

Guidance literature:: 6-hydroxy-3-hexynoic acid; With dicarbonylacetylacetonato rhodium (I); camphor-10-sulfonic acid; N-{6-[bis-(3’,5’-bis(trifluoromethyl)phenyl)phosphanyl]pyridine-2-carbonyl}guanidine; In 1,2-dichloro-ethane; for 0.166667h; Inert atmosphere;

carbon monoxide; With hydrogen; In 1,2-dichloro-ethane; at 55 ℃; for 20h; under 4500.45 Torr; regioselective reaction; Autoclave;
DOI:10.1002/anie.201809073

Reference yield:

: 3621-79-2
2-methyleneglutaric acid

: 122246-01-9
MH 031

Guidance literature:: Multi-step reaction with 4 steps

1: p-toluenesulfonic acid monohydrate / 48 h / 20 °C / Inert atmosphere

2: potassium carbonate / N,N-dimethyl-formamide / 20 °C / Inert atmosphere

3: tricyclohexylphosphine[1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-ylidine][benzylidene]ruthenium(II) dichloride / 1,2-dichloro-ethane / 12 h / Reflux; Inert atmosphere

4: lithium hydroxide / tetrahydrofuran; water / 8 h / 20 °C

With tricyclohexylphosphine[1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-ylidine][benzylidene]ruthenium(II) dichloride; p-toluenesulfonic acid monohydrate; potassium carbonate; lithium hydroxide; In tetrahydrofuran; water; 1,2-dichloro-ethane; N,N-dimethyl-formamide;
DOI:10.1016/j.tetlet.2014.09.088