1,4-dihydro-2-<(2-phthalimidoethoxy)methyl>-6-methyl-4-<3-(1H-imidazol-1-yl)phenyl>-3,5-pyridinedicarboxylic acid 3-ethyl 5-methyl ester

Base Information

Chemical Name:1,4-dihydro-2-<(2-phthalimidoethoxy)methyl>-6-methyl-4-<3-(1H-imidazol-1-yl)phenyl>-3,5-pyridinedicarboxylic acid 3-ethyl 5-methyl ester
CAS No.:148612-77-5
Molecular Formula:C₃₁H₃₀N₄O₇
Molecular Weight:570.602
Hs Code.:

Synonyms:1,4-dihydro-2-<(2-phthalimidoethoxy)methyl>-6-methyl-4-<3-(1H-imidazol-1-yl)phenyl>-3,5-pyridinedicarboxylic acid 3-ethyl 5-methyl ester

Suppliers and Price of 1,4-dihydro-2-<(2-phthalimidoethoxy)methyl>-6-methyl-4-<3-(1H-imidazol-1-yl)phenyl>-3,5-pyridinedicarboxylic acid 3-ethyl 5-methyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 1,4-dihydro-2-<(2-phthalimidoethoxy)methyl>-6-methyl-4-<3-(1H-imidazol-1-yl)phenyl>-3,5-pyridinedicarboxylic acid 3-ethyl 5-methyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 1,4-dihydro-2-<(2-phthalimidoethoxy)methyl>-6-methyl-4-<3-(1H-imidazol-1-yl)phenyl>-3,5-pyridinedicarboxylic acid 3-ethyl 5-methyl ester

There total 3 articles about 1,4-dihydro-2-<(2-phthalimidoethoxy)methyl>-6-methyl-4-<3-(1H-imidazol-1-yl)phenyl>-3,5-pyridinedicarboxylic acid 3-ethyl 5-methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 49.0%

: 14205-39-1
methyl (E)-3-aminocrotonate

: 88150-75-8
ethyl 4-[2-(phthalimido)ethoxy]acetoacetate

: 127404-22-2
3-(1H-imidazol-1-yl)-benzaldehyde

: 148612-77-5
1,4-dihydro-2-<(2-phthalimidoethoxy)methyl>-6-methyl-4-<3-(1H-imidazol-1-yl)phenyl>-3,5-pyridinedicarboxylic acid 3-ethyl 5-methyl ester

Guidance literature:: In ethanol; for 6h; Heating;
DOI:10.1021/jm00072a017

Reference yield:

: 17789-14-9
3-(1,3-dioxolan-2-yl)-phenylbromide

: 148612-77-5
1,4-dihydro-2-<(2-phthalimidoethoxy)methyl>-6-methyl-4-<3-(1H-imidazol-1-yl)phenyl>-3,5-pyridinedicarboxylic acid 3-ethyl 5-methyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: 1.) NaH, 2.) Cu / 1.) DMF, RT, 2.) DMF, 150 deg C, 4 h

2: 96 percent / 1 N aq. HCl / 2 h / Ambient temperature

3: 49 percent / ethanol / 6 h / Heating

With hydrogenchloride; copper; sodium hydride; In ethanol;
DOI:10.1021/jm00072a017

Reference yield:

: 151055-85-5
2-<3-(1H-imidazol-1-yl)phenyl>-1,3-dioxolane

: 148612-77-5
1,4-dihydro-2-<(2-phthalimidoethoxy)methyl>-6-methyl-4-<3-(1H-imidazol-1-yl)phenyl>-3,5-pyridinedicarboxylic acid 3-ethyl 5-methyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 96 percent / 1 N aq. HCl / 2 h / Ambient temperature

2: 49 percent / ethanol / 6 h / Heating

With hydrogenchloride; In ethanol;
DOI:10.1021/jm00072a017