Ethyl 4-(2-(1,3-dioxoisoindolin-2-yl)ethoxy)-3-oxobutanoate

Base Information

Chemical Name:Ethyl 4-(2-(1,3-dioxoisoindolin-2-yl)ethoxy)-3-oxobutanoate
CAS No.:88150-75-8
Molecular Formula:C16H17 N O6
Molecular Weight:319.314
Hs Code.:2925190090
European Community (EC) Number:618-122-3
DSSTox Substance ID:DTXSID90431687
Nikkaji Number:J1.650.305C
Wikidata:Q82245639
Mol file:88150-75-8.mol

Synonyms:88150-75-8;ethyl 4-(2-(1,3-dioxoisoindolin-2-yl)ethoxy)-3-oxobutanoate;ethyl 4-[2-(1,3-dioxoisoindol-2-yl)ethoxy]-3-oxobutanoate;Ethyl-4(2-Phthalimido Ethoxy)Acetoacetate;Ethyl 4-(2-phthalimidoethoxy)acetoacetate;MFCD12407176;ethyl 4-[2-(phthalimido)ethoxy]acetoacetate;ethyl 4-(2-(phthalimido)ethoxy)acetoacetate;SCHEMBL4985915;DTXSID90431687;RIGKLAOKQFKWNN-UHFFFAOYSA-N;Ethyl4-(2-(1,3-dioxoisoindolin-2-yl)ethoxy)-3-oxobutanoate;BCP33274;Ethyl 4-[2-(1,3-Dioxo-2-isoindolinyl)ethoxy]-3-oxobutanoate;AKOS015916097;AC-5611;DS-3729;SB66146;Ethyl-4-(2-phthalimidoethoxy)acetoacetate;SY271842;CS-0061613;W17210;4-(2-Phthalimidylethoxy)acetoacetic acid ethyl ester;4-[2-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-ethoxy]-3-oxo-butyric acid ethyl ester;Ethyl 4-[2-(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)ethoxy]-3-oxobutanoate;ethyl 4-[2-(1,3-dioxo-1,3-dihydro-2h-isoindol-2-yl)ethoxyl]-3-oxobutanoate

Suppliers and Price of Ethyl 4-(2-(1,3-dioxoisoindolin-2-yl)ethoxy)-3-oxobutanoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4-(2-Phthalimidoethoxy)acetoaceticAcidEthylEster
250mg
$ 500.00

TRC
4-(2-Phthalimidoethoxy)acetoaceticAcidEthylEster
1g
$ 1000.00

Medical Isotopes, Inc.
4-(2-Phthalimidoethoxy)acetoaceticAcidEthylEster
250 mg
$ 975.00

Medical Isotopes, Inc.
4-(2-Phthalimidoethoxy)acetoaceticAcidEthylEster
25 mg
$ 625.00

Crysdot
Ethyl4-(2-(1,3-dioxoisoindolin-2-yl)ethoxy)-3-oxobutanoate 95+%
5g
$ 1250.00

Crysdot
Ethyl4-(2-(1,3-dioxoisoindolin-2-yl)ethoxy)-3-oxobutanoate 95+%
1g
$ 370.00

ChemScene
Ethyl4-[2-(1,3-dioxoisoindol-2-yl)ethoxy]-3-oxobutanoate
1g
$ 300.00

ChemScene
Ethyl4-[2-(1,3-dioxoisoindol-2-yl)ethoxy]-3-oxobutanoate
250mg
$ 136.00

ChemScene
Ethyl4-[2-(1,3-dioxoisoindol-2-yl)ethoxy]-3-oxobutanoate
100mg
$ 85.00

American Custom Chemicals Corporation
ETHYL-4-(2-(1,3-DIOXOISOINDOLIN-2-YL)ETHOXY)-3-OXOBUTANOATE 95.00%
5MG
$ 497.12

Total 81 raw suppliers

Chemical Property of Ethyl 4-(2-(1,3-dioxoisoindolin-2-yl)ethoxy)-3-oxobutanoate

Chemical Property:

Boiling Point:479.7±30.0 °C(Predicted)
PKA:9.83±0.46(Predicted)
PSA：89.98000
Density:1.297±0.06 g/cm3(Predicted)
LogP:0.75940
Storage Temp.:2-8°C
Solubility.:Chloroform (Slightly), DMSO (Sparingly), Methanol (Sparingly)
XLogP3:0.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:9
Exact Mass:319.10558726
Heavy Atom Count:23
Complexity:465

Purity/Quality:

99% ^*data from raw suppliers

4-(2-Phthalimidoethoxy)acetoaceticAcidEthylEster ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)CC(=O)COCCN1C(=O)C2=CC=CC=C2C1=O
Uses 4-(2-Phthalimidoethoxy)acetoacetic Acid Ethyl Ester is an intermediate in the synthesis of Amlodipine Besilate (A633500) related compounds.

Technology Process of Ethyl 4-(2-(1,3-dioxoisoindolin-2-yl)ethoxy)-3-oxobutanoate

There total 7 articles about Ethyl 4-(2-(1,3-dioxoisoindolin-2-yl)ethoxy)-3-oxobutanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.9%