1-Benzyl-2-oxocyclohexanecarbonitrile

Base Information

• Chemical Name: 1-Benzyl-2-oxocyclohexanecarbonitrile
• CAS No.: 81418-21-5
• Molecular Formula: C₁₄H₁₅NO
• Molecular Weight: 213.279
• Mol file: 81418-21-5.mol

Synonyms:1-benzyl-2-oxo-cyclohexanecarbonitrile

Chemical Property of 1-Benzyl-2-oxocyclohexanecarbonitrile

Chemical Property:

Purity/Quality:

98% ^*data from raw suppliers

1-Benzyl-2-oxocyclohexanecarbonitrile 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-Benzyl-2-oxocyclohexanecarbonitrile

There total 2 articles about 1-Benzyl-2-oxocyclohexanecarbonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

benzyl bromide (100-39-0) → 1-benzyl-2-oxo-cyclohexanecarbonitrile (81418-21-5)

Guidance literature:

With ethanol;

Reference yield:

2-benzylcyclohexan-1-one (946-33-8) + P-toluenesulfonyl cyanide (19158-51-1) → 1-benzyl-2-oxo-cyclohexanecarbonitrile (81418-21-5) + 3-Benzyl-2-oxo-cyclohexanecarbonitrile (81418-20-4)

Guidance literature:

Yield given. Multistep reaction. Yields of byproduct given;

DOI:10.1016/S0040-4039(01)92406-2

Reference yield: 87.0%

Phenylselenyl bromide (34837-55-3) + 1-benzyl-2-oxo-cyclohexanecarbonitrile (81418-21-5) → C19H20OSe

Guidance literature:

1-benzyl-2-oxo-cyclohexanecarbonitrile; With naphthalen-1-yl-lithium; In tetrahydrofuran; at -40 ℃; for 0.333333h;

Phenylselenyl bromide; In tetrahydrofuran; at -40 ℃; for 0.5h; Further stages.;

DOI:10.1055/s-2007-977448

upstream raw materials:

2-benzylcyclohexan-1-one

P-toluenesulfonyl cyanide

benzyl bromide

Downstream raw materials:

2-benzyl-2-cyclohexenone

(E)-2-benzylidenecyclohexanone

Refernces