4-(diethylamino)-3-ethylbenzaldehyde

Base Information

• Chemical Name: 4-(diethylamino)-3-ethylbenzaldehyde
• CAS No.: 1427716-62-8
• Molecular Formula: C₁₃H₁₉NO
• Molecular Weight: 205.3
• Mol file: 1427716-62-8.mol

Synonyms:4-(diethylamino)-3-ethylbenzaldehyde

Chemical Property of 4-(diethylamino)-3-ethylbenzaldehyde

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-(diethylamino)-3-ethylbenzaldehyde

There total 5 articles about 4-(diethylamino)-3-ethylbenzaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

4-bromo-N,N,2-triethylaniline (81090-39-3) + N,N-dimethyl-formamide (68-12-2,33513-42-7) → 4-(diethylamino)-3-ethylbenzaldehyde (1427716-62-8)

Guidance literature:

With trichlorophosphate; at 0 - 60 ℃; for 4.66667h; Inert atmosphere;

DOI:10.1002/poc.2978

Reference yield:

N-(4-bromo-2-ethylphenyl)acetamide (51688-73-4) → 4-(diethylamino)-3-ethylbenzaldehyde (1427716-62-8)

Guidance literature:

Multi-step reaction with 3 steps

1: lithium aluminium tetrahydride / tetrahydrofuran / Inert atmosphere; Reflux

2: potassium carbonate / N,N-dimethyl-formamide / 48 h / 70 °C

3: trichlorophosphate / 4.67 h / 0 - 60 °C / Inert atmosphere

With lithium aluminium tetrahydride; potassium carbonate; trichlorophosphate; In tetrahydrofuran; N,N-dimethyl-formamide;

DOI:10.1002/poc.2978

Reference yield:

4-bromo-N,2-diethylaniline (81090-37-1) → 4-(diethylamino)-3-ethylbenzaldehyde (1427716-62-8)

Guidance literature:

Multi-step reaction with 2 steps

1: potassium carbonate / N,N-dimethyl-formamide / 48 h / 70 °C

2: trichlorophosphate / 4.67 h / 0 - 60 °C / Inert atmosphere

With potassium carbonate; trichlorophosphate; In N,N-dimethyl-formamide;

DOI:10.1002/poc.2978

upstream raw materials:

N-(4-bromo-2-ethylphenyl)acetamide

4-bromo-N,2-diethylaniline

4-bromo-N,N,2-triethylaniline

N,N-dimethyl-formamide

Downstream raw materials:

(E,E)-2,5-bis[2-(3-ethyl-4-N,N-diethylaminophenyl)ethenyl]pyrazine