4-bromo-N,N,2-triethylbenzenamine

Base Information

• Chemical Name: 4-bromo-N,N,2-triethylbenzenamine
• CAS No.: 81090-39-3
• Molecular Formula: C12H18BrN
• Molecular Weight: 256.186
• Mol file: 81090-39-3.mol

Synonyms:4-bromo-N,N,2-triethylbenzenamine

Chemical Property of 4-bromo-N,N,2-triethylbenzenamine

Chemical Property:

• PSA: 3.24000
• LogP: 3.85770

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-bromo-N,N,2-triethylbenzenamine

There total 4 articles about 4-bromo-N,N,2-triethylbenzenamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

4-bromo-N,2-diethylaniline (81090-37-1) + ethyl iodide (75-03-6) → 4-bromo-N,N,2-triethylaniline (81090-39-3)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; at 70 ℃; for 48h;

DOI:10.1002/poc.2978

Reference yield: 88.0%

→ 4-bromo-N,N,2-triethylaniline (81090-39-3)

Guidance literature:

Reference yield:

N-(4-bromo-2-ethylphenyl)acetamide (51688-73-4) → 4-bromo-N,N,2-triethylaniline (81090-39-3)

Guidance literature:

Multi-step reaction with 2 steps

1: lithium aluminium tetrahydride / tetrahydrofuran / Inert atmosphere; Reflux

2: potassium carbonate / N,N-dimethyl-formamide / 48 h / 70 °C

With lithium aluminium tetrahydride; potassium carbonate; In tetrahydrofuran; N,N-dimethyl-formamide;

DOI:10.1002/poc.2978

upstream raw materials:

N-(4-bromo-2-ethylphenyl)acetamide

4-bromo-N,2-diethylaniline

ethyl iodide

ortho-ethylaniline

Downstream raw materials:

(E,E)-2,5-bis[2-(3-ethyl-4-N,N-diethylaminophenyl)ethenyl]pyrazine

4-(diethylamino)-3-ethylbenzaldehyde