C₁₉H₂₈N₂O₂

Base Information

• Chemical Name: C₁₉H₂₈N₂O₂
• CAS No.: 1182178-42-2
• Molecular Formula: C₁₉H₂₈N₂O₂
• Molecular Weight: 316.444
• Mol file: 1182178-42-2.mol

Synonyms:C₁₉H₂₈N₂O₂

Chemical Property of C₁₉H₂₈N₂O₂

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

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Technology Process of C₁₉H₂₈N₂O₂

There total 1 articles about C₁₉H₂₈N₂O₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

Succinimide (123-56-8,89963-74-6) + formaldehyd (50-00-0,30525-89-4,61233-19-0) + 2,5-di-tert-butylaniline (21860-03-7) → C19H28N2O2 (1182178-42-2)

Guidance literature:

In ethanol; water; Reflux;

DOI:10.1039/c0cc04416d

Reference yield: 99.0%

C19H28N2O2 (1182178-42-2) → 2,5-di-tert-butyl-N-methylaniline

Guidance literature:

With sodium tetrahydroborate; In dimethyl sulfoxide; at 80 ℃; for 0.75h; Inert atmosphere;

DOI:10.1039/c0cc04416d

Reference yield:

C19H28N2O2 (1182178-42-2) → C23H29NO2

Guidance literature:

Multi-step reaction with 3 steps

1: sodium tetrahydroborate / dimethyl sulfoxide / 80 °C / Inert atmosphere

2: sodium carbonate / dichloromethane / 20 - 23 °C / Inert atmosphere

3: Regis_.(R). PIRKLE COVALENT (R,R) WHELK-01 / hexane; isopropyl alcohol / Resolution of racemate

With sodium tetrahydroborate; sodium carbonate; In hexane; dichloromethane; dimethyl sulfoxide; isopropyl alcohol;

DOI:10.1021/ja9050586

upstream raw materials:

Succinimide

formaldehyd

2,5-di-tert-butylaniline

Downstream raw materials:

C₂₂H₂₉NO₂

C₂₃H₂₉NO₂

C₁₉H₂₉NO₂

C₂₃H₄₁NO₂Si

Refernces

• 1、 Ayitou, Anoklase Jean-Luc,Sivaguru. "Reactive spin state dependent enantiospecific photocyclization of axially chiral α-substituted acrylanilides". supporting information; experimental part. p. 2568 - 2570. Retrieved 2011/04/26.