1-(phenyloxycarbonyl)-4,5,6-trihydro-piperidin-2-diphenylphosphinate

Base Information

• Chemical Name: 1-(phenyloxycarbonyl)-4,5,6-trihydro-piperidin-2-diphenylphosphinate
• CAS No.: 1097200-63-9
• Molecular Formula: C₂₄H₂₂NO₄P
• Molecular Weight: 419.417
• Mol file: 1097200-63-9.mol

Synonyms:1-(phenyloxycarbonyl)-4,5,6-trihydro-piperidin-2-diphenylphosphinate

Chemical Property of 1-(phenyloxycarbonyl)-4,5,6-trihydro-piperidin-2-diphenylphosphinate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-(phenyloxycarbonyl)-4,5,6-trihydro-piperidin-2-diphenylphosphinate

There total 1 articles about 1-(phenyloxycarbonyl)-4,5,6-trihydro-piperidin-2-diphenylphosphinate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 61.0%

N-(phenyloxycarbonyl)piperidin-2-one (164732-57-4) + Diphenylphosphinic chloride (1499-21-4) → 1-(phenyloxycarbonyl)-4,5,6-trihydro-piperidin-2-diphenylphosphinate (1097200-63-9)

Guidance literature:

N-(phenyloxycarbonyl)piperidin-2-one; With N,N,N,N,-tetramethylethylenediamine; lithium diisopropyl amide; In tetrahydrofuran; at -78 ℃; Inert atmosphere;

Diphenylphosphinic chloride; In tetrahydrofuran; at -78 - 20 ℃; Inert atmosphere;

DOI:10.1039/b809577a

Reference yield: 10.0%

1-(phenyloxycarbonyl)-4,5,6-trihydro-piperidin-2-diphenylphosphinate (1097200-63-9) + 4-methylphenylboronic acid (5720-05-8) → C19H19NO2 (1207685-04-8)

Guidance literature:

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium hydrogencarbonate; In 1,2-dimethoxyethane; water; at 85 ℃; Inert atmosphere;

DOI:10.1039/b809577a

Reference yield: 10.0%

1-(phenyloxycarbonyl)-4,5,6-trihydro-piperidin-2-diphenylphosphinate (1097200-63-9) + 4-methoxyphenylboronic acid (5720-07-0) → phenyl 6-(p-methoxyphenyl)-3,4-dihydro-1(2H)-pyridinecarboxylate

Guidance literature:

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium hydrogencarbonate; In 1,2-dimethoxyethane; water; at 85 ℃; Inert atmosphere;

DOI:10.1039/b809577a

upstream raw materials:

N-(phenyloxycarbonyl)piperidin-2-one

Diphenylphosphinic chloride

Downstream raw materials:

C₁₉H₁₉NO₂