2-[(4-Methoxy-benzenesulfonyl)-pyridin-3-ylmethyl-amino]-3,5-dimethylbenzoic acid

Base Information

• Chemical Name: 2-[(4-Methoxy-benzenesulfonyl)-pyridin-3-ylmethyl-amino]-3,5-dimethylbenzoic acid
• CAS No.: 206547-69-5
• Molecular Formula: C₂₂H₂₂N₂O₅S
• Molecular Weight: 426.493
• Mol file: 206547-69-5.mol

Synonyms:2-[(4-Methoxy-benzenesulfonyl)-pyridin-3-ylmethyl-amino]-3,5-dimethylbenzoic acid

Chemical Property of 2-[(4-Methoxy-benzenesulfonyl)-pyridin-3-ylmethyl-amino]-3,5-dimethylbenzoic acid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-[(4-Methoxy-benzenesulfonyl)-pyridin-3-ylmethyl-amino]-3,5-dimethylbenzoic acid

There total 6 articles about 2-[(4-Methoxy-benzenesulfonyl)-pyridin-3-ylmethyl-amino]-3,5-dimethylbenzoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

nicotinyl chloride (3099-31-8) → 2-[(4-Methoxy-benzenesulfonyl)-pyridin-3-ylmethyl-amino]-3,5-dimethylbenzoic acid (206547-69-5)

Guidance literature:

Multi-step reaction with 2 steps

1: NaH

2: NaOH

With sodium hydroxide; sodium hydride;

DOI:10.1016/S0960-894X(01)00419-X

Reference yield:

2-[(4-Methoxy-benzenesulfonyl)-pyridin-3-ylmethyl-amino]-3,5-dimethyl-benzoic acid methyl ester (206547-68-4) → 2-[(4-Methoxy-benzenesulfonyl)-pyridin-3-ylmethyl-amino]-3,5-dimethylbenzoic acid (206547-69-5)

Guidance literature:

With sodium hydroxide;

DOI:10.1016/S0960-894X(01)00419-X

Reference yield:

methyl 2-amino-3,5-dimethylbenzoate (206551-23-7) → 2-[(4-Methoxy-benzenesulfonyl)-pyridin-3-ylmethyl-amino]-3,5-dimethylbenzoic acid (206547-69-5)

Guidance literature:

Multi-step reaction with 3 steps

1: TEA

2: NaH

3: NaOH

With sodium hydroxide; TEA; sodium hydride;

DOI:10.1016/S0960-894X(01)00419-X

upstream raw materials:

2-[(4-Methoxy-benzenesulfonyl)-pyridin-3-ylmethyl-amino]-3,5-dimethyl-benzoic acid methyl ester

nicotinyl chloride

methyl 2-amino-3,5-dimethylbenzoate

4-methoxy-phenyl-sulphonyl chloride