ethyl 4-azido-3-O-benzyl-4,6-dideoxy-2-O-methyl-α-D-mannopyranosyl-(1->2)-4-azido-3-O-benzyl-4,6-dideoxy-1-thio-α-D-mannopyranoside

Base Information

• Chemical Name: ethyl 4-azido-3-O-benzyl-4,6-dideoxy-2-O-methyl-α-D-mannopyranosyl-(1->2)-4-azido-3-O-benzyl-4,6-dideoxy-1-thio-α-D-mannopyranoside
• CAS No.: 935678-46-9
• Molecular Formula: C₂₉H₃₈N₆O₆S
• Molecular Weight: 598.723
• Mol file: 935678-46-9.mol

Synonyms:ethyl 4-azido-3-O-benzyl-4,6-dideoxy-2-O-methyl-α-D-mannopyranosyl-(1->2)-4-azido-3-O-benzyl-4,6-dideoxy-1-thio-α-D-mannopyranoside

Chemical Property of ethyl 4-azido-3-O-benzyl-4,6-dideoxy-2-O-methyl-α-D-mannopyranosyl-(1->2)-4-azido-3-O-benzyl-4,6-dideoxy-1-thio-α-D-mannopyranoside

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of ethyl 4-azido-3-O-benzyl-4,6-dideoxy-2-O-methyl-α-D-mannopyranosyl-(1->2)-4-azido-3-O-benzyl-4,6-dideoxy-1-thio-α-D-mannopyranoside

There total 1 articles about ethyl 4-azido-3-O-benzyl-4,6-dideoxy-2-O-methyl-α-D-mannopyranosyl-(1->2)-4-azido-3-O-benzyl-4,6-dideoxy-1-thio-α-D-mannopyranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

ethyl 4-azido-3-O-benzyl-4,6-dideoxy-α-D-mannopyranosyl-(1->2)-4-azido-3-O-benzyl-4,6-dideoxy-1-thio-α-D-mannopyranoside (848828-33-1) + methyl iodide (74-88-4) → ethyl 4-azido-3-O-benzyl-4,6-dideoxy-2-O-methyl-α-D-mannopyranosyl-(1->2)-4-azido-3-O-benzyl-4,6-dideoxy-1-thio-α-D-mannopyranoside (935678-46-9)

Guidance literature:

With potassium hydroxide; In dimethyl sulfoxide; for 1h;

DOI:10.1002/ejoc.200600851

Reference yield: 97.0%

ethyl 4-azido-3-O-benzyl-4,6-dideoxy-2-O-methyl-α-D-mannopyranosyl-(1->2)-4-azido-3-O-benzyl-4,6-dideoxy-1-thio-α-D-mannopyranoside (935678-46-9) → ethyl 4-amino-3-O-benzyl-4,6-dideoxy-2-O-methyl-α-D-mannopyranosyl-(1->2)-4-amino-3-O-benzyl-4,6-dideoxy-1-thio-α-D-mannopyranoside (935678-47-0)

Guidance literature:

With hydrogen sulfide; In pyridine; water; at 40 ℃;

DOI:10.1002/ejoc.200600851

Reference yield:

ethyl 4-azido-3-O-benzyl-4,6-dideoxy-2-O-methyl-α-D-mannopyranosyl-(1->2)-4-azido-3-O-benzyl-4,6-dideoxy-1-thio-α-D-mannopyranoside (935678-46-9) → ethyl 3-O-benzyl-4-(2,4-di-O-acetyl-3-deoxy-L-glycero-tetronamido)-4,6-dideoxy-2-O-methyl-α-D-mannopyranosyl-(1->2)-3-O-benzyl-4-(2,4-di-O-acetyl-3-deoxy-L-glycero-tetronamido)-4,6-dideoxy-1-thio-α-D-mannopyranoside

Guidance literature:

Multi-step reaction with 2 steps

1: 97 percent / H₂S / pyridine; H₂O / 40 °C

2: 90 percent / EDAC / CH₂Cl₂ / 2 h

With hydrogen sulfide; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In pyridine; dichloromethane; water;

DOI:10.1002/ejoc.200600851

upstream raw materials:

ethyl 4-azido-3-O-benzyl-4,6-dideoxy-α-D-mannopyranosyl-(1->2)-4-azido-3-O-benzyl-4,6-dideoxy-1-thio-α-D-mannopyranoside

methyl iodide

Downstream raw materials:

ethyl 4-amino-3-O-benzyl-4,6-dideoxy-2-O-methyl-α-D-mannopyranosyl-(1->2)-4-amino-3-O-benzyl-4,6-dideoxy-1-thio-α-D-mannopyranoside