Technology Process of C26H18FN3O2
There total 7 articles about C26H18FN3O2 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
tetrakis(triphenylphosphine) palladium(0); potassium carbonate;
In
N,N-dimethyl-formamide;
at 80 ℃;
for 3h;
DOI:10.1055/s-0030-1260304
- Guidance literature:
-
Multi-step reaction with 3 steps
1: trimethylsilyl trifluoromethanesulfonate; N-ethyl-N,N-diisopropylamine / 1,2-dichloro-ethane / 120 h / 90 °C / Inert atmosphere
2: sodium hydride / tetrahydrofuran / 20 °C
3: tetrakis(triphenylphosphine) palladium(0); potassium carbonate / N,N-dimethyl-formamide / 3 h / 80 °C
With
tetrakis(triphenylphosphine) palladium(0); trimethylsilyl trifluoromethanesulfonate; sodium hydride; potassium carbonate; N-ethyl-N,N-diisopropylamine;
In
tetrahydrofuran; 1,2-dichloro-ethane; N,N-dimethyl-formamide;
3: Suzuki coupling;
DOI:10.1055/s-0030-1260304
- Guidance literature:
-
Multi-step reaction with 4 steps
1: dichloromethane / 0 - 20 °C
2: trimethylsilyl trifluoromethanesulfonate; N-ethyl-N,N-diisopropylamine / 1,2-dichloro-ethane / 120 h / 90 °C / Inert atmosphere
3: sodium hydride / tetrahydrofuran / 20 °C
4: tetrakis(triphenylphosphine) palladium(0); potassium carbonate / N,N-dimethyl-formamide / 3 h / 80 °C
With
tetrakis(triphenylphosphine) palladium(0); trimethylsilyl trifluoromethanesulfonate; sodium hydride; potassium carbonate; N-ethyl-N,N-diisopropylamine;
In
tetrahydrofuran; dichloromethane; 1,2-dichloro-ethane; N,N-dimethyl-formamide;
4: Suzuki coupling;
DOI:10.1055/s-0030-1260304
