3-(Pentamethylphenyl)-1-propanol

Base Information

• Chemical Name: 3-(Pentamethylphenyl)-1-propanol
• CAS No.: 5743-66-8
• Molecular Formula: C₁₄H₂₂O
• Molecular Weight: 206.328
• Mol file: 5743-66-8.mol

Synonyms:3-(Pentamethylphenyl)-1-propanol

Chemical Property of 3-(Pentamethylphenyl)-1-propanol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-(Pentamethylphenyl)-1-propanol

There total 7 articles about 3-(Pentamethylphenyl)-1-propanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

3-(2,3,4,5,6-pentamethylphenyl)propanoic acid (5743-69-1) → 3-(Pentamethylphenyl)-1-propanol (5743-66-8)

Guidance literature:

With lithium aluminium tetrahydride; In tetrahydrofuran; for 2h; Heating;

Reference yield:

Pentamethyl-dihydro-zimtsaeure-ethylester (5743-65-7) → 3-(Pentamethylphenyl)-1-propanol (5743-66-8)

Guidance literature:

With lithium aluminium tetrahydride; In diethyl ether;

Reference yield:

2,3,4,5,6-pentamethylbenzyl chloride (484-65-1) → 3-(Pentamethylphenyl)-1-propanol (5743-66-8)

Guidance literature:

Multi-step reaction with 7 steps

1: dimethylsulfoxide / 5 h / 130 °C / high pressure

2: H₂SO₄, H₂O / 10 h / 130 °C

3: 69 percent / LiAlH₄ / tetrahydrofuran / 2 h / Heating

4: HCl, ZnCl₂ / 14 h / 130 °C / high pressure

5: 87 percent / dimethylsulfoxide; H₂O / 4 h / 130 °C / high pressure

6: 80 percent / 45percent H₂SO₄ / 14 h / 130 °C / high pressure

7: 80 percent / LiAlH₄ / tetrahydrofuran / 2 h / Heating

With hydrogenchloride; lithium aluminium tetrahydride; sulfuric acid; water; zinc(II) chloride; In tetrahydrofuran; water; dimethyl sulfoxide;

upstream raw materials:

Pentamethyl-dihydro-zimtsaeure-ethylester

3-(2,3,4,5,6-pentamethylphenyl)propanoic acid

2,3,4,5,6-pentamethylbenzyl chloride

Pentamethylphenylacetic Acid

Downstream raw materials:

1-(3-Chloropropyl)-2,3,4,5,6-pentamethylbenzene