1,2-bis(2-{4'-[4'-(methylphenyl)sulphonyl]-1',7'-dioxa-4',10'-diazacyclododecane}ethoxy)-4,5-dinitrobenzene

Base Information

• Chemical Name: 1,2-bis(2-{4'-[4'-(methylphenyl)sulphonyl]-1',7'-dioxa-4',10'-diazacyclododecane}ethoxy)-4,5-dinitrobenzene
• CAS No.: 952658-45-6
• Molecular Formula: C₄₀H₅₆N₆O₁₄S₂
• Molecular Weight: 909.048
• Mol file: 952658-45-6.mol

Synonyms:1,2-bis(2-{4'-[4'-(methylphenyl)sulphonyl]-1',7'-dioxa-4',10'-diazacyclododecane}ethoxy)-4,5-dinitrobenzene

Chemical Property of 1,2-bis(2-{4'-[4'-(methylphenyl)sulphonyl]-1',7'-dioxa-4',10'-diazacyclododecane}ethoxy)-4,5-dinitrobenzene

Chemical Property:

Purity/Quality:

Safty Information:

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• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1,2-bis(2-{4'-[4'-(methylphenyl)sulphonyl]-1',7'-dioxa-4',10'-diazacyclododecane}ethoxy)-4,5-dinitrobenzene

There total 1 articles about 1,2-bis(2-{4'-[4'-(methylphenyl)sulphonyl]-1',7'-dioxa-4',10'-diazacyclododecane}ethoxy)-4,5-dinitrobenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

1,2-dinitro-4,5-bis(2-iodoethoxy)benzene + 4-[(4-methylphenyl)sulfonyl]-1,7-dioxa-4,10-diazacyclododecane (96563-15-4) → 1,2-bis(2-{4'-[4'-(methylphenyl)sulphonyl]-1',7'-dioxa-4',10'-diazacyclododecane}ethoxy)-4,5-dinitrobenzene (952658-45-6)

Guidance literature:

4-[(4-methylphenyl)sulfonyl]-1,7-dioxa-4,10-diazacyclododecane; With sodium carbonate; sodium iodide; In acetonitrile; at 45 ℃; for 0.5h; Inert atmosphere;

1,2-dinitro-4,5-bis(2-iodoethoxy)benzene; In acetonitrile; at 95 ℃; for 144h; Inert atmosphere;

DOI:10.1246/bcsj.80.1549

Reference yield: 87.5%

1,2-bis(2-{4'-[4'-(methylphenyl)sulphonyl]-1',7'-dioxa-4',10'-diazacyclododecane}ethoxy)-4,5-dinitrobenzene (952658-45-6) → 1,2-bis(2-{4'-[4'-(methylphenyl)sulfonyl]-1',7'-dioxa-4',10'-diazacyclododecane}ethoxy)-4,5-diaminobenzene (952658-49-0)

Guidance literature:

With 10% palladium on charcoal; hydrazine hydrate; In butan-1-ol; for 10.5h; Reflux; Inert atmosphere;

DOI:10.1246/bcsj.80.1549

upstream raw materials:

4-[(4-methylphenyl)sulfonyl]-1,7-dioxa-4,10-diazacyclododecane

Downstream raw materials:

1,2-bis(2-{4'-[4'-(methylphenyl)sulfonyl]-1',7'-dioxa-4',10'-diazacyclododecane}ethoxy)-4,5-diaminobenzene