Technology Process of 2-[4-(hexyloxy)phenyl]benzoxazol-5-ol
There total 7 articles about 2-[4-(hexyloxy)phenyl]benzoxazol-5-ol which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
potassium hydroxide;
In
tetrahydrofuran; ethanol; water;
at 20 ℃;
for 2h;
DOI:10.1002/hlca.200690035
- Guidance literature:
-
Multi-step reaction with 7 steps
1: 88 percent / Et3N / tetrahydrofuran / 0.5 h / 20 °C
2: 99 percent / cyclohexene / Pd(OH)2/C / ethanol / 2 h / Heating
3: 76 percent / NaNO3; Ac2O; HCl / CH2Cl2; diethyl ether; H2O / 4 h / 20 °C
4: cyclohexene / Pd(OH)2/C / ethanol / Heating
5: acetic acid / ethanol / Heating
6: 85 percent / 4,5-dichloro-3,6-dioxocyclohexa-1,4-diene-1,2-dicarbonitrile; 4 Angstroem molecular sieves / toluene / 2 h / Heating
7: 86 percent / KOH / ethanol; tetrahydrofuran; H2O / 2 h / 20 °C
With
hydrogenchloride; potassium hydroxide; sodium nitrate; 4 A molecular sieve; acetic anhydride; acetic acid; triethylamine; 2,3-dicyano-5,6-dichloro-p-benzoquinone; cyclohexene;
palladium dihydroxide;
In
tetrahydrofuran; diethyl ether; ethanol; dichloromethane; water; toluene;
DOI:10.1002/hlca.200690035
- Guidance literature:
-
Multi-step reaction with 4 steps
1: cyclohexene / Pd(OH)2/C / ethanol / Heating
2: acetic acid / ethanol / Heating
3: 85 percent / 4,5-dichloro-3,6-dioxocyclohexa-1,4-diene-1,2-dicarbonitrile; 4 Angstroem molecular sieves / toluene / 2 h / Heating
4: 86 percent / KOH / ethanol; tetrahydrofuran; H2O / 2 h / 20 °C
With
potassium hydroxide; 4 A molecular sieve; acetic acid; 2,3-dicyano-5,6-dichloro-p-benzoquinone; cyclohexene;
palladium dihydroxide;
In
tetrahydrofuran; ethanol; water; toluene;
DOI:10.1002/hlca.200690035