Technology Process of 2-formyl-3,4-dimethylphenyltrifluoromethanesulfonate
There total 7 articles about 2-formyl-3,4-dimethylphenyltrifluoromethanesulfonate which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
pyridine;
In
dichloromethane;
at 0 - 20 ℃;
for 1h;
Inert atmosphere;
DOI:10.1002/chem.201002817
- Guidance literature:
-
Multi-step reaction with 7 steps
1.1: bromine / dichloromethane / 1 h / 0 °C
2.1: potassium carbonate / acetone / 3 h / Reflux
3.1: diethylaluminium chloride / hexane / 6 h / 20 °C
4.1: potassium tert-butylate / tetrahydrofuran / 48 h / 20 °C
5.1: ozone / dichloromethane / -78 °C
5.2: 12 h / -78 - 20 °C
6.1: palladium on carbon; hydrogen; triethylamine / methanol / 2 h / 20 °C
7.1: pyridine / dichloromethane / 1 h / 0 - 20 °C / Inert atmosphere
With
pyridine; palladium on carbon; potassium tert-butylate; hydrogen; bromine; diethylaluminium chloride; potassium carbonate; ozone; triethylamine;
In
tetrahydrofuran; methanol; hexane; dichloromethane; acetone;
3.1: Claisen rearrangement;
DOI:10.1002/chem.201002817
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: ozone / dichloromethane / -78 °C
1.2: 12 h / -78 - 20 °C
2.1: palladium on carbon; hydrogen; triethylamine / methanol / 2 h / 20 °C
3.1: pyridine / dichloromethane / 1 h / 0 - 20 °C / Inert atmosphere
With
pyridine; palladium on carbon; hydrogen; ozone; triethylamine;
In
methanol; dichloromethane;
DOI:10.1002/chem.201002817
