tert-butyl 4-(2-(4-(7-chlorothieno[3,2-b]pyridin-2-yl)-1H-imidazol-1-yl)ethyl)piperazine-1-carboxylate

Base Information

Chemical Name:tert-butyl 4-(2-(4-(7-chlorothieno[3,2-b]pyridin-2-yl)-1H-imidazol-1-yl)ethyl)piperazine-1-carboxylate
CAS No.:1342836-83-2
Molecular Formula:C₂₁H₂₆ClN₅O₂S
Molecular Weight:447.989
Hs Code.:

Synonyms:tert-butyl 4-(2-(4-(7-chlorothieno[3,2-b]pyridin-2-yl)-1H-imidazol-1-yl)ethyl)piperazine-1-carboxylate

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Chemical Property of tert-butyl 4-(2-(4-(7-chlorothieno[3,2-b]pyridin-2-yl)-1H-imidazol-1-yl)ethyl)piperazine-1-carboxylate

Chemical Property:

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Technology Process of tert-butyl 4-(2-(4-(7-chlorothieno[3,2-b]pyridin-2-yl)-1H-imidazol-1-yl)ethyl)piperazine-1-carboxylate

There total 1 articles about tert-butyl 4-(2-(4-(7-chlorothieno[3,2-b]pyridin-2-yl)-1H-imidazol-1-yl)ethyl)piperazine-1-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 69627-03-8
7-chlorothieno[3,2-b]pyridine

palladium tetrakistriphenylphosphine: palladium tetrakistriphenylphosphine

: 1342836-78-5
tert-butyl 4-(2-(4-iodo-1H-imidazol-1-yl)ethyl)piperazine-1-carboxylate

: 1342836-83-2
tert-butyl 4-(2-(4-(7-chlorothieno[3,2-b]pyridin-2-yl)-1H-imidazol-1-yl)ethyl)piperazine-1-carboxylate

Guidance literature:: With n-butyllithium; zinc(II) chloride; In tetrahydrofuran; diethyl ether; hexane;

Reference yield:

: 1341216-35-0
3-fluoro-4-hydroxybenzenaminium chloride

: 1342836-83-2
tert-butyl 4-(2-(4-(7-chlorothieno[3,2-b]pyridin-2-yl)-1H-imidazol-1-yl)ethyl)piperazine-1-carboxylate

: 399-96-2
4-amino-2-fluorophenol

: 1342836-88-7
tert-butyl 4-(2-(4-(7-(4-amino-2-fluorophenoxy)thieno[3,2-b]pyridin-2-yl)-1H-imidazol-1-yl)ethyl)piperazine-1-carboxylate

Guidance literature:: With hydrogenchloride; In potassium tert-butylate; water;

Reference yield:

: 1342836-83-2
tert-butyl 4-(2-(4-(7-chlorothieno[3,2-b]pyridin-2-yl)-1H-imidazol-1-yl)ethyl)piperazine-1-carboxylate

: 399-96-2
4-amino-2-fluorophenol

: 1342836-91-2
tert-butyl 4-(2-(4-(7-(4-(3-cyclopropylureido)-2-fluorophenoxy)thieno[3,2-b]pyridin-2-yl)-1H-imidazol-1-yl)ethyl)piperazine-1-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: hydrogenchloride / potassium tert-butylate; water

2: pyridine / N,N-dimethyl-formamide; water

With pyridine; hydrogenchloride; In potassium tert-butylate; water; N,N-dimethyl-formamide;