(2S,3R,6S)-6-(2-Benzyloxy-ethyl)-2-(1,1-dimethyl-allyl)-2,3-dimethoxy-tetrahydro-pyran

Base Information

Chemical Name:(2S,3R,6S)-6-(2-Benzyloxy-ethyl)-2-(1,1-dimethyl-allyl)-2,3-dimethoxy-tetrahydro-pyran
CAS No.:884345-85-1
Molecular Formula:C₂₁H₃₂O₄
Molecular Weight:348.483
Hs Code.:

Synonyms:(2S,3R,6S)-6-(2-Benzyloxy-ethyl)-2-(1,1-dimethyl-allyl)-2,3-dimethoxy-tetrahydro-pyran

Suppliers and Price of (2S,3R,6S)-6-(2-Benzyloxy-ethyl)-2-(1,1-dimethyl-allyl)-2,3-dimethoxy-tetrahydro-pyran

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (2S,3R,6S)-6-(2-Benzyloxy-ethyl)-2-(1,1-dimethyl-allyl)-2,3-dimethoxy-tetrahydro-pyran

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (2S,3R,6S)-6-(2-Benzyloxy-ethyl)-2-(1,1-dimethyl-allyl)-2,3-dimethoxy-tetrahydro-pyran

There total 12 articles about (2S,3R,6S)-6-(2-Benzyloxy-ethyl)-2-(1,1-dimethyl-allyl)-2,3-dimethoxy-tetrahydro-pyran which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 884345-69-1
(2S,3R,6S)-6-(2-Benzyloxy-ethyl)-2-(1,1-dimethyl-allyl)-2-methoxy-tetrahydro-pyran-3-ol

: 74-88-4
methyl iodide

: 884345-85-1
(2S,3R,6S)-6-(2-Benzyloxy-ethyl)-2-(1,1-dimethyl-allyl)-2,3-dimethoxy-tetrahydro-pyran

Guidance literature:: With sodium hydride; In N,N-dimethyl-formamide;
DOI:10.1016/j.tetlet.2006.01.097

Reference yield:

: 884345-81-7
(S)-1-benzyloxyhept-6-en-3-ol

: 884345-85-1
(2S,3R,6S)-6-(2-Benzyloxy-ethyl)-2-(1,1-dimethyl-allyl)-2,3-dimethoxy-tetrahydro-pyran

Guidance literature:: Multi-step reaction with 11 steps

1.1: 93 percent / imidazole

2.1: BH₃*THF

2.2: 86 percent / H₂O₂; NaOH

3.1: (COCl)2; DMSO; Et₃N

4.1: Zn

5.1: (COCl)2; DMSO; Et₃N

6.1: TBAF

7.1: 99 percent / camphor sulfonic acid; 4 Angstroem molecular sieves / benzene

8.1: mCPBA

9.1: Dess-Martin periodinane

10.1: 88 percent / LiBHEt₃

11.1: 87 percent / NaH / dimethylformamide

With 1H-imidazole; borane-THF; oxalyl dichloride; 4 A molecular sieve; camphor-10-sulfonic acid; tetrabutyl ammonium fluoride; sodium hydride; lithium triethylborohydride; Dess-Martin periodane; dimethyl sulfoxide; triethylamine; 3-chloro-benzenecarboperoxoic acid; zinc; In N,N-dimethyl-formamide; benzene; 3.1: Swern oxidation / 5.1: Swern oxidation / 9.1: Dess-Martin oxidation;
DOI:10.1016/j.tetlet.2006.01.097

Reference yield:

: 884345-67-9
2-(2-benzyloxy-ethyl)-6-(1,1-dimethyl-allyl)-3,4-dihydro-2H-pyran

: 884345-85-1
(2S,3R,6S)-6-(2-Benzyloxy-ethyl)-2-(1,1-dimethyl-allyl)-2,3-dimethoxy-tetrahydro-pyran

Guidance literature:: Multi-step reaction with 4 steps

1: mCPBA

2: Dess-Martin periodinane

3: 88 percent / LiBHEt₃

4: 87 percent / NaH / dimethylformamide

With sodium hydride; lithium triethylborohydride; Dess-Martin periodane; 3-chloro-benzenecarboperoxoic acid; In N,N-dimethyl-formamide; 2: Dess-Martin oxidation;
DOI:10.1016/j.tetlet.2006.01.097