2-(4-bromophenyl)-2-oxoethyl (1S,2S)-2-((tert-butoxycarbonyl)(ethyl)amino)cyclopentanecarboxylate

Base Information

Chemical Name:2-(4-bromophenyl)-2-oxoethyl (1S,2S)-2-((tert-butoxycarbonyl)(ethyl)amino)cyclopentanecarboxylate
CAS No.:1422429-02-4
Molecular Formula:C₂₁H₂₈BrNO₅
Molecular Weight:454.361
Hs Code.:

Synonyms:2-(4-bromophenyl)-2-oxoethyl (1S,2S)-2-((tert-butoxycarbonyl)(ethyl)amino)cyclopentanecarboxylate

Suppliers and Price of 2-(4-bromophenyl)-2-oxoethyl (1S,2S)-2-((tert-butoxycarbonyl)(ethyl)amino)cyclopentanecarboxylate

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2-(4-bromophenyl)-2-oxoethyl (1S,2S)-2-((tert-butoxycarbonyl)(ethyl)amino)cyclopentanecarboxylate

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

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Technology Process of 2-(4-bromophenyl)-2-oxoethyl (1S,2S)-2-((tert-butoxycarbonyl)(ethyl)amino)cyclopentanecarboxylate

There total 4 articles about 2-(4-bromophenyl)-2-oxoethyl (1S,2S)-2-((tert-butoxycarbonyl)(ethyl)amino)cyclopentanecarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

: 1422429-01-3
(1S,2S)-2-((tert-butoxycarbonyl)(ethyl)amino)cyclopentanecarboxylic acid

: 99-73-0,132309-76-3
para-bromophenacyl bromide

: 1422429-02-4
2-(4-bromophenyl)-2-oxoethyl (1S,2S)-2-((tert-butoxycarbonyl)(ethyl)amino)cyclopentanecarboxylate

Guidance literature:: With N-ethyl-N,N-diisopropylamine; at 20 - 40 ℃; for 3h;

Reference yield:

: 1422428-99-6
ethyl (1S,2S)-2-(ethylamino)cyclopentanecarboxylate

: 1422429-02-4
2-(4-bromophenyl)-2-oxoethyl (1S,2S)-2-((tert-butoxycarbonyl)(ethyl)amino)cyclopentanecarboxylate

Guidance literature:: Multi-step reaction with 3 steps

1: sodium hydrogencarbonate / 1,4-dioxane; water / 16 h / 20 - 40 °C

2: lithium hydroxide; water / tetrahydrofuran; ethanol / 4 h / 20 - 40 °C

3: N-ethyl-N,N-diisopropylamine / 3 h / 20 - 40 °C

With water; sodium hydrogencarbonate; N-ethyl-N,N-diisopropylamine; lithium hydroxide; In tetrahydrofuran; 1,4-dioxane; ethanol; water;

Reference yield:

: 1609100-30-2,752181-59-2
ethyl (1S,2S)-2-aminocyclopentanecarboxylate

: 1422429-02-4
2-(4-bromophenyl)-2-oxoethyl (1S,2S)-2-((tert-butoxycarbonyl)(ethyl)amino)cyclopentanecarboxylate

Guidance literature:: Multi-step reaction with 4 steps

1.1: acetic acid / tetrahydrofuran / 1 h / 20 - 40 °C

1.2: 16 h / 20 - 40 °C

2.1: sodium hydrogencarbonate / 1,4-dioxane; water / 16 h / 20 - 40 °C

3.1: lithium hydroxide; water / tetrahydrofuran; ethanol / 4 h / 20 - 40 °C

4.1: N-ethyl-N,N-diisopropylamine / 3 h / 20 - 40 °C

With water; sodium hydrogencarbonate; acetic acid; N-ethyl-N,N-diisopropylamine; lithium hydroxide; In tetrahydrofuran; 1,4-dioxane; ethanol; water;