(3aS,4S,7aR)-3a-((S)-2-Benzyloxy-2-methyl-pent-4-enyl)-4-(4-methoxy-benzyloxy)-2,2-dimethyl-hexahydro-benzo[1,3]dioxole

Base Information

Chemical Name:(3aS,4S,7aR)-3a-((S)-2-Benzyloxy-2-methyl-pent-4-enyl)-4-(4-methoxy-benzyloxy)-2,2-dimethyl-hexahydro-benzo[1,3]dioxole
CAS No.:314242-41-6
Molecular Formula:C₃₀H₄₀O₅
Molecular Weight:480.645
Hs Code.:

Synonyms:(3aS,4S,7aR)-3a-((S)-2-Benzyloxy-2-methyl-pent-4-enyl)-4-(4-methoxy-benzyloxy)-2,2-dimethyl-hexahydro-benzo[1,3]dioxole

Suppliers and Price of (3aS,4S,7aR)-3a-((S)-2-Benzyloxy-2-methyl-pent-4-enyl)-4-(4-methoxy-benzyloxy)-2,2-dimethyl-hexahydro-benzo[1,3]dioxole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (3aS,4S,7aR)-3a-((S)-2-Benzyloxy-2-methyl-pent-4-enyl)-4-(4-methoxy-benzyloxy)-2,2-dimethyl-hexahydro-benzo[1,3]dioxole

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (3aS,4S,7aR)-3a-((S)-2-Benzyloxy-2-methyl-pent-4-enyl)-4-(4-methoxy-benzyloxy)-2,2-dimethyl-hexahydro-benzo[1,3]dioxole

There total 6 articles about (3aS,4S,7aR)-3a-((S)-2-Benzyloxy-2-methyl-pent-4-enyl)-4-(4-methoxy-benzyloxy)-2,2-dimethyl-hexahydro-benzo[1,3]dioxole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 314242-20-1
(3aS,4S,7aR)-2,2-Dimethyl-3a-prop-2-ynyl-hexahydro-benzo[1,3]dioxol-4-ol

: 314242-41-6
(3aS,4S,7aR)-3a-((S)-2-Benzyloxy-2-methyl-pent-4-enyl)-4-(4-methoxy-benzyloxy)-2,2-dimethyl-hexahydro-benzo[1,3]dioxole

Guidance literature:: Multi-step reaction with 5 steps

1.1: 92 percent / NaH / dimethylformamide / 2 h / 0 °C

2.1: 97 percent / H₂; quinoline / Lindlar's catalyst / hexane / 1.17 h

3.1: Hg(OAc)2 / methanol / 1 h

3.2: 80 percent / PdCl₂; LiCl; CuCl₂ / 0.5 h

4.1: diethyl ether / -78 °C

5.1: 98 percent / KH; (n-Bu)4NI / dimethylformamide / 1.5 h / 0 °C

With quinoline; mercury(II) diacetate; hydrogen; tetra-(n-butyl)ammonium iodide; potassium hydride; sodium hydride; Lindlar's catalyst; In methanol; diethyl ether; hexane; N,N-dimethyl-formamide;
DOI:10.1016/S0040-4039(00)01479-9

Reference yield:

: 314242-19-8
Acetic acid (1S,2R,3R)-2,3-dihydroxy-2-prop-2-ynyl-cyclohexyl ester

: 314242-41-6
(3aS,4S,7aR)-3a-((S)-2-Benzyloxy-2-methyl-pent-4-enyl)-4-(4-methoxy-benzyloxy)-2,2-dimethyl-hexahydro-benzo[1,3]dioxole

Guidance literature:: Multi-step reaction with 7 steps

1.1: TsOH / benzene / 0.5 h

2.1: K₂CO₃ / methanol / 0.75 h

3.1: 92 percent / NaH / dimethylformamide / 2 h / 0 °C

4.1: 97 percent / H₂; quinoline / Lindlar's catalyst / hexane / 1.17 h

5.1: Hg(OAc)2 / methanol / 1 h

5.2: 80 percent / PdCl₂; LiCl; CuCl₂ / 0.5 h

6.1: diethyl ether / -78 °C

7.1: 98 percent / KH; (n-Bu)4NI / dimethylformamide / 1.5 h / 0 °C

With quinoline; mercury(II) diacetate; hydrogen; tetra-(n-butyl)ammonium iodide; potassium hydride; sodium hydride; potassium carbonate; toluene-4-sulfonic acid; Lindlar's catalyst; In methanol; diethyl ether; hexane; N,N-dimethyl-formamide; benzene;
DOI:10.1016/S0040-4039(00)01479-9

Reference yield:

: 392300-36-6
Acetic acid (3aR,4S,7aR)-2,2-dimethyl-3a-prop-2-ynyl-hexahydro-benzo[1,3]dioxol-4-yl ester

: 314242-41-6
(3aS,4S,7aR)-3a-((S)-2-Benzyloxy-2-methyl-pent-4-enyl)-4-(4-methoxy-benzyloxy)-2,2-dimethyl-hexahydro-benzo[1,3]dioxole

Guidance literature:: Multi-step reaction with 6 steps

1.1: K₂CO₃ / methanol / 0.75 h

2.1: 92 percent / NaH / dimethylformamide / 2 h / 0 °C

3.1: 97 percent / H₂; quinoline / Lindlar's catalyst / hexane / 1.17 h

4.1: Hg(OAc)2 / methanol / 1 h

4.2: 80 percent / PdCl₂; LiCl; CuCl₂ / 0.5 h

5.1: diethyl ether / -78 °C

6.1: 98 percent / KH; (n-Bu)4NI / dimethylformamide / 1.5 h / 0 °C

With quinoline; mercury(II) diacetate; hydrogen; tetra-(n-butyl)ammonium iodide; potassium hydride; sodium hydride; potassium carbonate; Lindlar's catalyst; In methanol; diethyl ether; hexane; N,N-dimethyl-formamide;
DOI:10.1016/S0040-4039(00)01479-9