Nebularine

Base Information

Chemical Name:Nebularine
CAS No.:550-33-4
Molecular Formula:C10H12 N4 O4
Molecular Weight:252.23
Hs Code.:2934999090
European Community (EC) Number:208-981-9
UNII:B8B604PS4P
DSSTox Substance ID:DTXSID701015580
Nikkaji Number:J1.609H
Wikidata:Q3874106
Metabolomics Workbench ID:51208
ChEMBL ID:CHEMBL1399702
Mol file:550-33-4.mol

Synonyms:9-(beta-D-ribofuranosyl)purine;nebularine;purine ribonucleoside;purine riboside;purine-1-D-ribofuranoside

Suppliers and Price of Nebularine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
Nebularine
50mg
$ 368.00

Usbiological
Nebularine
500ug
$ 325.00

Usbiological
Nebularine
100mg
$ 460.00

TRC
Nebularine
500mg
$ 625.00

Medical Isotopes, Inc.
9-(b-D-Ribofuranosyl)purine
50 mg
$ 385.00

Crysdot
(2R,3S,4R,5R)-2-(Hydroxymethyl)-5-(9H-purin-9-yl)tetrahydrofuran-3,4-diol 97%
100mg
$ 315.00

Crysdot
(2R,3S,4R,5R)-2-(Hydroxymethyl)-5-(9H-purin-9-yl)tetrahydrofuran-3,4-diol 97%
250mg
$ 500.00

Crysdot
(2R,3S,4R,5R)-2-(Hydroxymethyl)-5-(9H-purin-9-yl)tetrahydrofuran-3,4-diol 97%
1g
$ 1251.00

Chemenu
(2R,3S,4R,5R)-2-(hydroxymethyl)-5-(9H-purin-9-yl)tetrahydrofuran-3,4-diol 95%
1g
$ 1170.00

Biosynth Carbosynth
9-(b-D-Ribofuranosyl)purine
500 mg
$ 600.00

Total 29 raw suppliers

Chemical Property of Nebularine

Chemical Property:

Vapor Pressure:7.71E-15mmHg at 25°C
Melting Point:181-182°C
Refractive Index:1.6500 (estimate)
Boiling Point:591.6°Cat760mmHg
PKA:13.13±0.70(Predicted)
Flash Point:311.6°C
PSA：113.52000
Density:1.91g/cm³
LogP:-1.56220
Storage Temp.:2-8°C
Solubility.:DMSO (Slightly), Ethanol, Methanol (Slightly)
XLogP3:-0.7
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:2
Exact Mass:252.08585488
Heavy Atom Count:18
Complexity:308

Purity/Quality:

99% ^*data from raw suppliers

Nebularine ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi
Statements: 36/37/38
Safety Statements: 26-36

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Canonical SMILES:C1=C2C(=NC=N1)N(C=N2)C3C(C(C(O3)CO)O)O
Isomeric SMILES:C1=C2C(=NC=N1)N(C=N2)[C@H]3[C@@H]([C@@H]([C@H](O3)CO)O)O
Description This purine base is produced by Agarius nebularis Batsch. (Syn. Clitocybe nebularis). It is laevorotatory with [α]25D - 48.6° (c 1.0, H20).
Uses Nebularine is shown to have inhibitory effects against mouse Sarcoma 180 and mycobacteria.

Technology Process of Nebularine

There total 26 articles about Nebularine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

: 15981-63-2
2',3',5'-tri-O-acetylnebularine

: 550-33-4
Nebularin

Guidance literature:: With ammonia; In ethanol; for 48h; Ambient temperature;
DOI:10.1055/s-1984-30851

Reference yield: 82.0%

: 574-25-4
6-mercaptopurine riboside

: 550-33-4
Nebularin

Guidance literature:: With nitric acid; In water; at 50 ℃; for 1h; Temperature; Time; Concentration;
DOI:10.1080/10426507.2016.1225057

Reference yield: 80.0%

: 120-73-0
purine

: 58-96-8
uridine

: 550-33-4
Nebularin

Guidance literature:: With Enterobacter gergoviae CECT 875 in agar; In phosphate buffer; at 60 ℃; for 3h; pH=7.0; Enzymatic reaction;
DOI:10.1016/S0040-4039(03)00225-9