Technology Process of (2S,8R,Z)-7-benzyldimethylsilyl-8-hydroxy-11,11-dimethoxyundec-6-en-2-yl benzoate
There total 9 articles about (2S,8R,Z)-7-benzyldimethylsilyl-8-hydroxy-11,11-dimethoxyundec-6-en-2-yl benzoate which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
Wilkinson's catalyst; hydrogen;
In
tetrahydrofuran; tert-butyl alcohol;
at 20 ℃;
for 10h;
chemoselective reaction;
Inert atmosphere;
DOI:10.1021/ol300200m
- Guidance literature:
-
Multi-step reaction with 2 steps
1: tris(acetonitrile)pentamethylcyclopentadienylruthenium(II) hexafluorophosphate / 1,2-dichloro-ethane / 0 - 20 °C / Inert atmosphere
2: Wilkinson's catalyst; hydrogen / tetrahydrofuran; tert-butyl alcohol / 10 h / 20 °C / Inert atmosphere
With
Wilkinson's catalyst; tris(acetonitrile)pentamethylcyclopentadienylruthenium(II) hexafluorophosphate; hydrogen;
In
tetrahydrofuran; 1,2-dichloro-ethane; tert-butyl alcohol;
DOI:10.1021/ol300200m
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: dimethyl zinc(II); Triphenylphosphine oxide; ((2S,2'S)-((2-hydroxy-5-methyl-1,3-phenylene)bis(methylene))bis(pyrrolidine-1,2-diyl))bis(diphenylmethanol) / toluene / 0 - 20 °C / Inert atmosphere
1.2: 48 h / 0 - 4 °C / Inert atmosphere
2.1: tris(acetonitrile)pentamethylcyclopentadienylruthenium(II) hexafluorophosphate / 1,2-dichloro-ethane / 0 - 20 °C / Inert atmosphere
3.1: Wilkinson's catalyst; hydrogen / tetrahydrofuran; tert-butyl alcohol / 10 h / 20 °C / Inert atmosphere
With
Wilkinson's catalyst; tris(acetonitrile)pentamethylcyclopentadienylruthenium(II) hexafluorophosphate; hydrogen; dimethyl zinc(II); Triphenylphosphine oxide; ((2S,2'S)-((2-hydroxy-5-methyl-1,3-phenylene)bis(methylene))bis(pyrrolidine-1,2-diyl))bis(diphenylmethanol);
In
tetrahydrofuran; 1,2-dichloro-ethane; toluene; tert-butyl alcohol;
DOI:10.1021/ol300200m
