Technology Process of C19H27NSi
There total 3 articles about C19H27NSi which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
C13H13N;
With
n-butyllithium; diisopropylamine;
In
tetrahydrofuran; hexanes;
at -78 ℃;
for 0.166667h;
Inert atmosphere;
tert-butyldimethylsilyl chloride;
In
tetrahydrofuran; hexanes;
at -78 - 20 ℃;
for 3h;
Inert atmosphere;
DOI:10.1021/ol201566u
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: lithium hexamethyldisilazane / tetrahydrofuran / 0.17 h / -78 °C / Inert atmosphere
1.2: 15 h / -78 - 20 °C / Inert atmosphere
2.1: tetrakis(triphenylphosphine) palladium(0); sodium carbonate / water; toluene / 18 h / 20 - 70 °C / Inert atmosphere
3.1: n-butyllithium; diisopropylamine / tetrahydrofuran; hexanes / 0.17 h / -78 °C / Inert atmosphere
3.2: 3 h / -78 - 20 °C / Inert atmosphere
With
tetrakis(triphenylphosphine) palladium(0); n-butyllithium; sodium carbonate; diisopropylamine; lithium hexamethyldisilazane;
In
tetrahydrofuran; hexanes; water; toluene;
DOI:10.1021/ol201566u
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: tetrakis(triphenylphosphine) palladium(0); sodium carbonate / water; toluene / 18 h / 20 - 70 °C / Inert atmosphere
2.1: n-butyllithium; diisopropylamine / tetrahydrofuran; hexanes / 0.17 h / -78 °C / Inert atmosphere
2.2: 3 h / -78 - 20 °C / Inert atmosphere
With
tetrakis(triphenylphosphine) palladium(0); n-butyllithium; sodium carbonate; diisopropylamine;
In
tetrahydrofuran; hexanes; water; toluene;
DOI:10.1021/ol201566u
