Cholest-5-en-3β-yl 4-methoxymethoxybenzoate

Base Information

• Chemical Name: Cholest-5-en-3β-yl 4-methoxymethoxybenzoate
• CAS No.: 156539-49-0
• Molecular Formula: C₃₆H₅₄O₄
• Molecular Weight: 550.822
• Mol file: 156539-49-0.mol

Synonyms:Cholest-5-en-3β-yl 4-methoxymethoxybenzoate

Chemical Property of Cholest-5-en-3β-yl 4-methoxymethoxybenzoate

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of Cholest-5-en-3β-yl 4-methoxymethoxybenzoate

There total 2 articles about Cholest-5-en-3β-yl 4-methoxymethoxybenzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

cholesterol (57-88-5) + 4-(methoxymethoxy)benzoic acid methyl ester (139884-19-8) → Cholest-5-en-3β-yl 4-methoxymethoxybenzoate (156539-49-0)

Guidance literature:

With n-butyllithium; In tetrahydrofuran; hexane; 1.) 0 deg C, 15min, 2.) r.t., overnight;

DOI:10.1039/DT9940001051

Reference yield:

methyl 4-hydroxylbenzoate (99-76-3,156291-94-0) → Cholest-5-en-3β-yl 4-methoxymethoxybenzoate (156539-49-0)

Guidance literature:

Multi-step reaction with 2 steps

1: 89 percent / P₂O₅ / CH₂Cl₂ / Ambient temperature

2: 84 percent / butyllithium / hexane; tetrahydrofuran / 1.) 0 deg C, 15min, 2.) r.t., overnight

With n-butyllithium; phosphorus pentoxide; In tetrahydrofuran; hexane; dichloromethane;

DOI:10.1039/DT9940001051

Reference yield: 85.0%

Cholest-5-en-3β-yl 4-methoxymethoxybenzoate (156539-49-0) → Cholest-5-en-3β-yl 4-hydroxybenzoate (74754-58-8)

Guidance literature:

With hydrogenchloride; In tetrahydrofuran; acetic acid; for 8h; Ambient temperature;

DOI:10.1039/DT9940001051

upstream raw materials:

cholesterol

4-(methoxymethoxy)benzoic acid methyl ester

methyl 4-hydroxylbenzoate

Downstream raw materials:

Cholest-5-en-3β-yl 4-hydroxybenzoate