5,5-difluoro-8-formyl-1,3,7,9-tetramethyl-10-phenyl-5H-dipyrrolo[1,2-c:2',1'-f][1,3,2]diazaborinin-4-ium-5-uide

Base Information

• Chemical Name: 5,5-difluoro-8-formyl-1,3,7,9-tetramethyl-10-phenyl-5H-dipyrrolo[1,2-c:2',1'-f][1,3,2]diazaborinin-4-ium-5-uide
• CAS No.: 1189166-58-2
• Molecular Formula: C₂₀H₁₉BF₂N₂O
• Molecular Weight: 352.191
• Mol file: 1189166-58-2.mol

Synonyms:5,5-difluoro-8-formyl-1,3,7,9-tetramethyl-10-phenyl-5H-dipyrrolo[1,2-c:2',1'-f][1,3,2]diazaborinin-4-ium-5-uide

Chemical Property of 5,5-difluoro-8-formyl-1,3,7,9-tetramethyl-10-phenyl-5H-dipyrrolo[1,2-c:2',1'-f][1,3,2]diazaborinin-4-ium-5-uide

Chemical Property:

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 5,5-difluoro-8-formyl-1,3,7,9-tetramethyl-10-phenyl-5H-dipyrrolo[1,2-c:2',1'-f][1,3,2]diazaborinin-4-ium-5-uide

There total 14 articles about 5,5-difluoro-8-formyl-1,3,7,9-tetramethyl-10-phenyl-5H-dipyrrolo[1,2-c:2',1'-f][1,3,2]diazaborinin-4-ium-5-uide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

N,N-dimethyl-formamide (68-12-2,33513-42-7) + phenyl BODIPY → 5,5-difluoro-8-formyl-1,3,7,9-tetramethyl-10-phenyl-5H-dipyrrolo[1,2-c:2',1'-f][1,3,2]diazaborinin-4-ium-5-uide (1189166-58-2)

Guidance literature:

With trichlorophosphate; at 60 ℃; for 3h;

DOI:10.1007/s10895-017-2200-5

Reference yield:

C26H23BF2N6O4 → 5,5-difluoro-8-formyl-1,3,7,9-tetramethyl-10-phenyl-5H-dipyrrolo[1,2-c:2',1'-f][1,3,2]diazaborinin-4-ium-5-uide (1189166-58-2)

Guidance literature:

With hypochlorite; In aq. phosphate buffer; N,N-dimethyl-formamide; pH=7.4;

DOI:10.1016/j.jphotochem.2017.10.037

Reference yield:

2,4-dimethyl-1H-pyrrole (625-82-1) → 5,5-difluoro-8-formyl-1,3,7,9-tetramethyl-10-phenyl-5H-dipyrrolo[1,2-c:2',1'-f][1,3,2]diazaborinin-4-ium-5-uide (1189166-58-2)

Guidance literature:

Multi-step reaction with 2 steps

1: dichloromethane

2: trichlorophosphate / 60 °C

With trichlorophosphate; In dichloromethane; 2: |Vilsmeier-Haack Formylation;

DOI:10.1039/c3cc44463e

upstream raw materials:

N,N-dimethyl-formamide

2,4-dimethyl-1H-pyrrole

benzoyl chloride

benzaldehyde

Downstream raw materials:

C₂₅H₂₅BF₂N₂O₃

(C₉HN₂BF₂)(CH₃)4(C₆H₅)(CHC(CN)2)

5,5-difluoro-8-formyl-2-iodo-1,3,7,9-tetramethyl-10-phenyl-5H-dipyrrolo[1,2-c:2',1'-f][1,3,2]diazaborinin-4-ium-5-uide

2-(4-(diphenylamino)phenyl)-5,5-difluoro-8-formyl-1,3,7,9-tetramethyl-10-phenyl-5H-dipyrrolo[1,2-c:2',1'-f][1,3,2]diazaborinin-4-ium-5-uide