2,2'-(ethane-1,2-diyl)bis(4-methoxyaniline)

Base Information

• Chemical Name: 2,2'-(ethane-1,2-diyl)bis(4-methoxyaniline)
• CAS No.: 383860-02-4
• Molecular Formula: C₁₆H₂₀N₂O₂
• Molecular Weight: 272.347
• Mol file: 383860-02-4.mol

Synonyms:2,2'-(ethane-1,2-diyl)bis(4-methoxyaniline)

Chemical Property of 2,2'-(ethane-1,2-diyl)bis(4-methoxyaniline)

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2,2'-(ethane-1,2-diyl)bis(4-methoxyaniline)

There total 4 articles about 2,2'-(ethane-1,2-diyl)bis(4-methoxyaniline) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

5,5'-dimethoxy-2,2'-dinitrobibenzyl (383860-01-3) → 2,2'-(ethane-1,2-diyl)bis(4-methoxyaniline) (383860-02-4)

Guidance literature:

With hydrazine hydrate; 10percent Pd/C; In ethanol; for 2h; Heating;

DOI:10.1021/jm010016f

Reference yield: 83.0%

1,2-bis(5-methoxy-2-nitrophenyl)ethyne → 2,2'-(ethane-1,2-diyl)bis(4-methoxyaniline) (383860-02-4)

Guidance literature:

With palladium 10% on activated carbon; hydrogen; In methanol; dichloromethane;

DOI:10.1021/jacs.9b08794

Reference yield:

5-methoxy-2-nitrotoluene (5367-32-8) → 2,2'-(ethane-1,2-diyl)bis(4-methoxyaniline) (383860-02-4)

Guidance literature:

Multi-step reaction with 2 steps

1: 64 percent / potassium tert-butoxide / dimethylsulfoxide; diethyl ether / 3.75 h / -10 - 20 °C

2: 98 percent / hydrazine hydrate / 10percent Pd/C / aq. ethanol / 2 h / Heating

With potassium tert-butylate; hydrazine hydrate; 10percent Pd/C; In diethyl ether; ethanol; dimethyl sulfoxide;

DOI:10.1021/jm010016f

upstream raw materials:

5,5'-dimethoxy-2,2'-dinitrobibenzyl

5-methoxy-2-nitrotoluene

3-iodo-4-nitroanisol

Downstream raw materials:

5,5'-dimethoxy-2,2'-dinitrosobibenzyl