Technology Process of tert-butyl 6-(benzyloxy)-2-((4-(4-methylpiperazin-1-yl)phenyl)diazenyl)-9H-purine-9-carboxylate
There total 6 articles about tert-butyl 6-(benzyloxy)-2-((4-(4-methylpiperazin-1-yl)phenyl)diazenyl)-9H-purine-9-carboxylate which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
acetic acid;
In
dichloromethane;
at 20 ℃;
for 24h;
DOI:10.1021/jm301804p
- Guidance literature:
-
Multi-step reaction with 5 steps
1: dmap / dichloromethane / 16 h / 20 °C
2: tetrabutylammonium nitrate; trifluoroacetic anhydride / dichloromethane / 1 h / 0 °C
3: 10% Pt/activated carbon; hydrogen; acetic acid / ethyl acetate; methanol / 0.5 h / 20 °C / 760.05 Torr
4: sodium periodate / dichloromethane; water / 2 h / 0 °C
5: acetic acid / dichloromethane / 24 h / 20 °C
With
dmap; sodium periodate; 10% Pt/activated carbon; hydrogen; tetrabutylammonium nitrate; acetic acid; trifluoroacetic anhydride;
In
methanol; dichloromethane; water; ethyl acetate;
DOI:10.1021/jm301804p
- Guidance literature:
-
Multi-step reaction with 5 steps
1: dmap / dichloromethane / 16 h / 20 °C
2: tetrabutylammonium nitrate; trifluoroacetic anhydride / dichloromethane / 1 h / 0 °C
3: 10% Pt/activated carbon; hydrogen; acetic acid / ethyl acetate; methanol / 0.5 h / 20 °C / 760.05 Torr
4: sodium periodate / dichloromethane; water / 2 h / 0 °C
5: acetic acid / dichloromethane / 24 h / 20 °C
With
dmap; sodium periodate; 10% Pt/activated carbon; hydrogen; tetrabutylammonium nitrate; acetic acid; trifluoroacetic anhydride;
In
methanol; dichloromethane; water; ethyl acetate;
DOI:10.1021/jm301804p
