4-Imidazo[1,2-a]pyrimidin-2-ylbenzaldehyde

Base Information

Chemical Name:4-Imidazo[1,2-a]pyrimidin-2-ylbenzaldehyde
CAS No.:118001-70-0
Molecular Formula:C₁₃H₉N₃O
Molecular Weight:223.234
Hs Code.:
DSSTox Substance ID:DTXSID001268336

Synonyms:4-imidazo[1,2-a]pyrimidin-2-ylbenzaldehyde;SCHEMBL1428800;UYQVESWAEZEPPY-UHFFFAOYSA-N;DTXSID001268336;118001-70-0

Suppliers and Price of 4-Imidazo[1,2-a]pyrimidin-2-ylbenzaldehyde

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 4-Imidazo[1,2-a]pyrimidin-2-ylbenzaldehyde

Chemical Property:

XLogP3:2.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:223.074561919
Heavy Atom Count:17
Complexity:276

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CN2C=C(N=C2N=C1)C3=CC=C(C=C3)C=O

Technology Process of 4-Imidazo[1,2-a]pyrimidin-2-ylbenzaldehyde

There total 4 articles about 4-Imidazo[1,2-a]pyrimidin-2-ylbenzaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 42.0%

: 104691-51-2
2-(4-Cyano-phenyl)-imidazo[1,2-a]pyrimidine

: 118001-70-0
4-imidazo[1,2-a]pyrimidin-2-ylbenzaldehyde

Guidance literature:: With sodium hypophosphite; Ra-Ni; In pyridine; water; acetic acid; at 100 ℃; for 7h;
DOI:10.1002/jhet.5570250119

Reference yield:

: 109-12-6
2-aminopyrimidine

: 951656-07-8
α-bromo-4-formylacetophenone

: 118001-70-0
4-imidazo[1,2-a]pyrimidin-2-ylbenzaldehyde

Guidance literature:: In acetone;

Reference yield:

: 118001-69-7
2-(4-iodophenyl)imidazo[1,2-a]pyrimidine

: 118001-70-0
4-imidazo[1,2-a]pyrimidin-2-ylbenzaldehyde

Guidance literature:: Multi-step reaction with 2 steps

1: 69 percent / dimethylformamide / 24 h / Heating

2: 42 percent / sodium hypophosphite hydrate / Ra-Ni / H₂O; acetic acid; pyridine / 7 h / 100 °C

With sodium hypophosphite; Ra-Ni; In pyridine; water; acetic acid; N,N-dimethyl-formamide;
DOI:10.1002/jhet.5570250119