4-benzyloxy-3,5-dihydroxybenzaldehyde

Base Information

• Chemical Name: 4-benzyloxy-3,5-dihydroxybenzaldehyde
• CAS No.: 161192-74-1
• Molecular Formula: C₁₄H₁₂O₄
• Molecular Weight: 244.247
• Mol file: 161192-74-1.mol

Synonyms:4-benzyloxy-3,5-dihydroxybenzaldehyde

Chemical Property of 4-benzyloxy-3,5-dihydroxybenzaldehyde

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-benzyloxy-3,5-dihydroxybenzaldehyde

There total 1 articles about 4-benzyloxy-3,5-dihydroxybenzaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

gallaldehyde (13677-79-7) + benzyl chloride (100-44-7) → 4-benzyloxy-3,5-dihydroxybenzaldehyde (161192-74-1)

Guidance literature:

With potassium carbonate; potassium iodide; In acetone; Heating;

DOI:10.1039/a803281e

Reference yield: 80.0%

ethyl bromoacetate (105-36-2) + 4-benzyloxy-3,5-dihydroxybenzaldehyde (161192-74-1) → C22H24O8

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; at 50 ℃; for 5h; Inert atmosphere;

DOI:10.1002/cjoc.202100013

Reference yield:

4-benzyloxy-3,5-dihydroxybenzaldehyde (161192-74-1) → C11H10O8

Guidance literature:

Multi-step reaction with 2 steps

1: potassium carbonate / N,N-dimethyl-formamide / 5 h / 50 °C / Inert atmosphere

2: amberlyst-15 / methanol; toluene / 100 °C

With potassium carbonate; In methanol; N,N-dimethyl-formamide; toluene;

DOI:10.1002/cjoc.202100013

upstream raw materials:

gallaldehyde

benzyl chloride

Downstream raw materials:

ethyl 4-hydroxy-3,5-bis((⁽²⁾H₃)methoxy)cinnamate