Technology Process of C33H58O5SSi
There total 3 articles about C33H58O5SSi which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 3 steps
1: potassium osmate(VI) dihydrate; methanesulfonamide; water; potassium carbonate; 4-[(R)-[(2R,4R,5S)-5-ethyl-1-azabicyclo[2.2.2]octan-2-yl]-(6-methoxy-4-quinolinyl)methoxy]-1-[(R)-[(2R,4S,5R)-5-ethyl-1-azabicyclo[2.2.2]octan-2-yl]-(6-methoxy-4-quinolinyl)methoxy]phthalazine; potassium hexacyanoferrate(III) / tert-butyl alcohol / 22 h / 0 - 10 °C
2: lithium borohydride; water / tetrahydrofuran
3: sodium hydride / tetrahydrofuran
With
potassium osmate(VI) dihydrate; lithium borohydride; methanesulfonamide; water; sodium hydride; potassium carbonate; 4-[(R)-[(2R,4R,5S)-5-ethyl-1-azabicyclo[2.2.2]octan-2-yl]-(6-methoxy-4-quinolinyl)methoxy]-1-[(R)-[(2R,4S,5R)-5-ethyl-1-azabicyclo[2.2.2]octan-2-yl]-(6-methoxy-4-quinolinyl)methoxy]phthalazine; potassium hexacyanoferrate(III);
In
tetrahydrofuran; tert-butyl alcohol;
1: Sharpless dihydroxylation / 3: Fraser-Reid epoxidation;
DOI:10.1016/j.tetlet.2010.11.013
- Guidance literature:
-
Multi-step reaction with 2 steps
1: lithium borohydride; water / tetrahydrofuran
2: sodium hydride / tetrahydrofuran
With
lithium borohydride; water; sodium hydride;
In
tetrahydrofuran;
2: Fraser-Reid epoxidation;
DOI:10.1016/j.tetlet.2010.11.013
