5-(2-cyanoacrylic acid-3-yl)-3,4-dioctyloxythiophene-2-carbaldehyde-N,N-diphenylhydrazone

Base Information

• Chemical Name: 5-(2-cyanoacrylic acid-3-yl)-3,4-dioctyloxythiophene-2-carbaldehyde-N,N-diphenylhydrazone
• CAS No.: 1351758-12-7
• Molecular Formula: C₃₇H₄₇N₃O₄S
• Molecular Weight: 629.864
• Mol file: 1351758-12-7.mol

Synonyms:5-(2-cyanoacrylic acid-3-yl)-3,4-dioctyloxythiophene-2-carbaldehyde-N,N-diphenylhydrazone

Chemical Property of 5-(2-cyanoacrylic acid-3-yl)-3,4-dioctyloxythiophene-2-carbaldehyde-N,N-diphenylhydrazone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 5-(2-cyanoacrylic acid-3-yl)-3,4-dioctyloxythiophene-2-carbaldehyde-N,N-diphenylhydrazone

There total 6 articles about 5-(2-cyanoacrylic acid-3-yl)-3,4-dioctyloxythiophene-2-carbaldehyde-N,N-diphenylhydrazone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

5-formyl-3,4-dioctyloxythiophene-2-carbaldehyde-N,N-diphenylhydrazone (1351758-08-1) + cyanoacetic acid (372-09-8) → 5-(2-cyanoacrylic acid-3-yl)-3,4-dioctyloxythiophene-2-carbaldehyde-N,N-diphenylhydrazone (1351758-12-7)

Guidance literature:

With piperidine; In acetonitrile; at 80 ℃; for 24h; Inert atmosphere;

DOI:10.1016/j.dyepig.2011.08.014

Reference yield:

3,4-dioctyloxythiophene-2-carbaldehyde (1299492-28-6) → 5-(2-cyanoacrylic acid-3-yl)-3,4-dioctyloxythiophene-2-carbaldehyde-N,N-diphenylhydrazone (1351758-12-7)

Guidance literature:

Multi-step reaction with 3 steps

1: sodium acetate / tetrahydrofuran; methanol / 24 h / Inert atmosphere; Reflux

2: trichlorophosphate / 4.5 h / 20 °C / Inert atmosphere; Reflux

3: piperidine / acetonitrile / 24 h / 80 °C / Inert atmosphere

With piperidine; sodium acetate; trichlorophosphate; In tetrahydrofuran; methanol; acetonitrile;

DOI:10.1016/j.dyepig.2011.08.014

Reference yield:

2,3-dimethoxythiophene (51792-34-8) → 5-(2-cyanoacrylic acid-3-yl)-3,4-dioctyloxythiophene-2-carbaldehyde-N,N-diphenylhydrazone (1351758-12-7)

Guidance literature:

Multi-step reaction with 5 steps

1: toluene-4-sulfonic acid / 24 h / 90 °C

2: trichlorophosphate / 4.5 h / 20 °C / Inert atmosphere; Reflux

3: sodium acetate / tetrahydrofuran; methanol / 24 h / Inert atmosphere; Reflux

4: trichlorophosphate / 4.5 h / 20 °C / Inert atmosphere; Reflux

5: piperidine / acetonitrile / 24 h / 80 °C / Inert atmosphere

With piperidine; sodium acetate; toluene-4-sulfonic acid; trichlorophosphate; In tetrahydrofuran; methanol; acetonitrile;

DOI:10.1016/j.dyepig.2011.08.014

upstream raw materials:

2,3-dimethoxythiophene

3,4-dioctyloxythiophene-2-carbaldehyde-N,N-diphenylhydrazone

5-formyl-3,4-dioctyloxythiophene-2-carbaldehyde-N,N-diphenylhydrazone

cyanoacetic acid

Refernces