2,3-diamino-5,6,7,8-tetrahydro-5,5,8,8-tetramethyl naphthalene

Base Information

• Chemical Name: 2,3-diamino-5,6,7,8-tetrahydro-5,5,8,8-tetramethyl naphthalene
• CAS No.: 81864-05-3
• Molecular Formula: C₁₄H₂₂N₂
• Molecular Weight: 218.342
• Mol file: 81864-05-3.mol

Synonyms:2,3-diamino-5,6,7,8-tetrahydro-5,5,8,8-tetramethyl naphthalene

Chemical Property of 2,3-diamino-5,6,7,8-tetrahydro-5,5,8,8-tetramethyl naphthalene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2,3-diamino-5,6,7,8-tetrahydro-5,5,8,8-tetramethyl naphthalene

There total 1 articles about 2,3-diamino-5,6,7,8-tetrahydro-5,5,8,8-tetramethyl naphthalene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.5%

1,1,4,4-Tetramethyl-1,2,3,4-tetrahydro-naphthalene (6683-46-1) → 5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthylamine (92050-16-3) + 2,3-diamino-5,6,7,8-tetrahydro-5,5,8,8-tetramethyl naphthalene (81864-05-3)

Guidance literature:

1,1,4,4-Tetramethyl-1,2,3,4-tetrahydro-naphthalene; With sulfuric acid; hydroxylamine hydrochloride; In acetonitrile; at 25 ℃; for 0.166667h;

With hydrogenchloride; titanium(III) chloride; In water; acetonitrile; at 25 ℃; Inert atmosphere; Sealed tube;

DOI:10.1021/acs.orglett.0c00598

Reference yield: 96.0%

benzenesulfonyl chloride (98-09-9) + 2,3-diamino-5,6,7,8-tetrahydro-5,5,8,8-tetramethyl naphthalene (81864-05-3) → 2,3-bis(N-benzenesulfonylamino)-5,6,7,8-tetrahydro-5,5,8,8-tetramethylnaphthalene

Guidance literature:

With pyridine; In dichloromethane; at 0 ℃; for 2h;

DOI:10.1021/ol035509o

Reference yield: 70.0%

2,3-diamino-5,6,7,8-tetrahydro-5,5,8,8-tetramethyl naphthalene (81864-05-3) + ethyl <4-(methoxycarbonyl)benzoyl>acetate (155877-84-2) → methyl 4-(1H-2,3,7,8,9,10-hexahydro-7,7,10,10-tetramethyl-2-oxonaphtho<2,3-b><1,4>diazepin-4-yl)benzoate (155877-85-3)

Guidance literature:

In xylene; at 140 ℃; for 1.5h;

DOI:10.1021/jm00036a017

upstream raw materials:

1,1,4,4-Tetramethyl-1,2,3,4-tetrahydro-naphthalene

Downstream raw materials:

methyl 4-(1H-2,3,7,8,9,10-hexahydro-7,7,10,10-tetramethyl-2-oxonaphtho<2,3-b><1,4>diazepin-4-yl)benzoate

methyl 4-(1H-2,3,7,8,9,10-hexahydro-1,7,7,10,10-pentamethyl-2-oxonaphtho<2,3-b><1,4>diazepin-4-yl)benzoate

Refernces