1-[[[(1R)-1-[3-[(1E)-2-(7-chloro-2-quinolinyl)ethenyl]phenyl]-3-[2-(1-hydroxy-1-methylethyl)phenyl]propyl]sulfanyl]methyl]cyclopropaneacetic acid L-(+)-treo-2-amino-1-phenyl-1,3-propanediol salt

Base Information

• Chemical Name: 1-[[[(1R)-1-[3-[(1E)-2-(7-chloro-2-quinolinyl)ethenyl]phenyl]-3-[2-(1-hydroxy-1-methylethyl)phenyl]propyl]sulfanyl]methyl]cyclopropaneacetic acid L-(+)-treo-2-amino-1-phenyl-1,3-propanediol salt
• CAS No.: 1005743-14-5
• Molecular Formula: C₉H₁₃NO₂*C₃₅H₃₆ClNO₃S
• Molecular Weight: 753.402
• Mol file: 1005743-14-5.mol

Synonyms:1-[[[(1R)-1-[3-[(1E)-2-(7-chloro-2-quinolinyl)ethenyl]phenyl]-3-[2-(1-hydroxy-1-methylethyl)phenyl]propyl]sulfanyl]methyl]cyclopropaneacetic acid L-(+)-treo-2-amino-1-phenyl-1,3-propanediol salt

Chemical Property of 1-[[[(1R)-1-[3-[(1E)-2-(7-chloro-2-quinolinyl)ethenyl]phenyl]-3-[2-(1-hydroxy-1-methylethyl)phenyl]propyl]sulfanyl]methyl]cyclopropaneacetic acid L-(+)-treo-2-amino-1-phenyl-1,3-propanediol salt

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

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Technology Process of 1-[[[(1R)-1-[3-[(1E)-2-(7-chloro-2-quinolinyl)ethenyl]phenyl]-3-[2-(1-hydroxy-1-methylethyl)phenyl]propyl]sulfanyl]methyl]cyclopropaneacetic acid L-(+)-treo-2-amino-1-phenyl-1,3-propanediol salt

There total 1 articles about 1-[[[(1R)-1-[3-[(1E)-2-(7-chloro-2-quinolinyl)ethenyl]phenyl]-3-[2-(1-hydroxy-1-methylethyl)phenyl]propyl]sulfanyl]methyl]cyclopropaneacetic acid L-(+)-treo-2-amino-1-phenyl-1,3-propanediol salt which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

(1S,2S)-2-amino-1-phenyl-1,3-diol (28143-91-1) + montelukast (158966-92-8) → 1-[[[(1R)-1-[3-[(1E)-2-(7-chloro-2-quinolinyl)ethenyl]phenyl]-3-[2-(1-hydroxy-1-methylethyl)phenyl]propyl]sulfanyl]methyl]cyclopropaneacetic acid L-(+)-treo-2-amino-1-phenyl-1,3-propanediol salt (1005743-14-5)

Guidance literature:

In toluene; at 20 ℃; for 18h; Product distribution / selectivity;

upstream raw materials:

(1S,2S)-2-amino-1-phenyl-1,3-diol

montelukast