Montelukast

Base Information Edit

Chemical Name:Montelukast
CAS No.:158966-92-8
Molecular Formula:C35H36ClNO3S
Molecular Weight:586.195
Hs Code.:
Mol file:158966-92-8.mol

Synonyms:Cyclopropaneaceticacid,1-[[[1-[3-[2-(7-chloro-2-quinolinyl)ethenyl]phenyl]-3-[2-(1-hydroxy-1-methylethyl)phenyl]propyl]thio]methyl]-,[R-(E)]-;1-[[[(R)-1-[3-[(E)-2-(7-Chloro-2-quinolinyl)ethenyl]phenyl]-3-[2-(1-hydroxy-1-methylethyl)phenyl]propyl]thio]methyl]cyclopropaneaceticacid;2-[1-[[[(1R)-1-[3-[(1E)-2-(7-Chloro-2-quinolinyl)ethenyl]phenyl]-3-[2-(1-hydroxy-1-methylethyl)phenyl]propyl]thio]methyl]cyclopropyl]aceticacid;[1-[[[(1R)-1-[3-[(E)-2-(7-Chloroquinolin-2-yl)vinyl]phenyl]-3-[2-(1-hydroxy-1-methylethyl)phenyl]propyl]sulfanyl]methyl]cyclopropyl]aceticacid;(R-(E))-1-(((1-(3-(2-(7-Chloro-2-quinolinyl)ethenyl)phenyl)-3-(2-(1-hydroxy-1-methylethyl)phenyl)propyl)thio)methyl)cyclopropaneacetic acid;

Suppliers and Price of Montelukast

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Medical Isotopes, Inc.
Montelukast-d6
1 mg
$ 715.00

Biosynth Carbosynth
Montelukast
100 mg
$ 135.00

Biosynth Carbosynth
Montelukast
25 mg
$ 54.00

Biorbyt Ltd
Montelukast >98%
250 mg
$ 455.60

Biorbyt Ltd
Montelukast >98%
50 mg
$ 173.40

AvaChem
Montelukast
100mg
$ 49.00

AvaChem
Montelukast
1g
$ 205.00

American Custom Chemicals Corporation
MONTELUKAST 95.00%
10MG
$ 588.19

American Custom Chemicals Corporation
MONTELUKAST 95.00%
100MG
$ 770.10

Ambeed
(R,E)-2-(1-(((1-(3-(2-(7-Chloroquinolin-2-yl)vinyl)phenyl)-3-(2-(2-hydroxypropan-2-yl)phenyl)propyl)thio)methyl)cyclopropyl)aceticacid 99%
5g
$ 932.00

Total 107 raw suppliers

Chemical Property of Montelukast Edit

Chemical Property:

Vapor Pressure:1.17E-23mmHg at 25°C
Melting Point:145-148 °C(Solv: toluene (108-88-3); methanol (67-56-1))
Refractive Index:1.677
Boiling Point:750.45 °C at 760 mmHg
PKA:4.76±0.10(Predicted)
Flash Point:407.658 °C
Density:1.272 g/cm³

Purity/Quality:

99% ^*data from raw suppliers

Montelukast-d6 ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses cardiostimulant,
Therapeutic Function Anti-asthmatic
Clinical Use Leukotriene receptor antagonist: Prophylaxis of asthma Seasonal allergic rhinitis
Drug interactions Potentially hazardous interactions with other drugs None known

Technology Process of Montelukast

There total 113 articles about Montelukast which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.7%

: 1-(mercaptomethyl)cyclopropane acetic acid disodium salt

: C₃₅H₃₁ClNO₅P

: 158966-92-8
montelukast

Guidance literature:: 1-(mercaptomethyl)cyclopropane acetic acid disodium salt; C₃₅H₃₁ClNO₅P; With N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; at -5 - 20 ℃; Inert atmosphere;

With acetic acid; In tetrahydrofuran; at -5 - 0 ℃; pH=2 - 3;