Alphacetylmethadol

Base Information

• Chemical Name: Alphacetylmethadol
• CAS No.: 17199-58-5
• Molecular Formula: C₂₃H₃₁NO₂
• Molecular Weight: 353.505
• Hs Code.: 2922199090
• UNII: BXF83S0HEL
• DSSTox Substance ID: DTXSID70169198
• Nikkaji Number: J9.669E
• Wikipedia: Alphacetylmethadol
• Wikidata: Q4735230
• NCI Thesaurus Code: C72134
• Metabolomics Workbench ID: 146203
• ChEMBL ID: CHEMBL2107793
• Mol file: 17199-58-5.mol

Synonyms:(3R,6R)-3-Acetoxy-6-dimethylamino-4,4-diphenylheptane;6-(Dimethylamino)-4,4-Diphenyl-3-Heptanol Acetate;Acemethadone;Acetylmethadol;Alphacetylmethadol;Amidolacetate;Dimepheptanol;LAAM;Levo alpha Acetylmethadol;Levo-alpha-Acetylmethadol;Levoacetylmethadol;Levomethadyl;Levomethadyl Acetate;Levomethadyl Acetate Hydrochloride;Methadol;Methadyl Acetate;ORLAAM

 This product is a nationally controlled contraband, and the Lookchem platform doesn't provide relevant sales information.

Chemical Property of Alphacetylmethadol

Chemical Property:

• Vapor Pressure: 1.68E-08mmHg at 25°C
• Boiling Point: 456°C at 760 mmHg
• Flash Point: 130°C
• PSA: 29.54000
• Density: 1.02g/cm³
• LogP: 4.65460
• XLogP3: 4.3
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 9
• Exact Mass: 353.235479232
• Heavy Atom Count: 26
• Complexity: 404

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCC(C(CC(C)N(C)C)(C1=CC=CC=C1)C2=CC=CC=C2)OC(=O)C
• Isomeric SMILES: CC[C@H](C(C[C@@H](C)N(C)C)(C1=CC=CC=C1)C2=CC=CC=C2)OC(=O)C

Technology Process of Alphacetylmethadol

There total 4 articles about Alphacetylmethadol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

acetic anhydride (108-24-7) → (+/-)-threo-5-acetoxy-2-dimethylamino-4,4-diphenyl-heptane (509-74-0,1477-40-3,1553-31-7,14623-72-4,17199-58-5,17199-59-6,66944-76-1,34433-66-4)

Guidance literature:

With pyridine;

DOI:10.1021/ja01170a025

Reference yield:

acetyl chloride (75-36-5) → (+/-)-threo-5-acetoxy-2-dimethylamino-4,4-diphenyl-heptane (509-74-0,1477-40-3,1553-31-7,14623-72-4,17199-58-5,17199-59-6,66944-76-1,34433-66-4)

Guidance literature:

With ethyl acetate;

DOI:10.1021/ja01169a016

Reference yield:

(+/-)-erythro-6-dimethylamino-4,4-diphenyl-heptan-3-ol (545-90-4,14019-10-4,15529-92-7,17199-54-1,17199-55-2,63869-11-4,86360-60-3) + acetic anhydride (108-24-7) → (+/-)-erythro-5-acetoxy-2-dimethylamino-4,4-diphenyl-heptane (509-74-0,1477-40-3,1553-31-7,14623-72-4,17199-58-5,17199-59-6,66944-76-1,34433-66-4)

Guidance literature:

upstream raw materials:

acetic anhydride

acetyl chloride

(+/-)-erythro-6-dimethylamino-4,4-diphenyl-heptan-3-ol

Downstream raw materials:

(+/-)-alpha-methadol

α-(+/-)-4,4-Diphenyl-6-keto-3-heptanol acetat

α-(+/-)-4,4-Diphenyl-6-oximino-3-heptanol acetat