1,2,3-Trimethoxy-5-[(E)-2-methylsulfanyl-2-(toluene-4-sulfonyl)-vinyl]-benzene

Base Information

• Chemical Name: 1,2,3-Trimethoxy-5-[(E)-2-methylsulfanyl-2-(toluene-4-sulfonyl)-vinyl]-benzene
• CAS No.: 107951-75-7
• Molecular Formula: C₁₉H₂₂O₅S₂
• Molecular Weight: 394.513
• Mol file: 107951-75-7.mol

Synonyms:1,2,3-Trimethoxy-5-[(E)-2-methylsulfanyl-2-(toluene-4-sulfonyl)-vinyl]-benzene

Chemical Property of 1,2,3-Trimethoxy-5-[(E)-2-methylsulfanyl-2-(toluene-4-sulfonyl)-vinyl]-benzene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1,2,3-Trimethoxy-5-[(E)-2-methylsulfanyl-2-(toluene-4-sulfonyl)-vinyl]-benzene

There total 1 articles about 1,2,3-Trimethoxy-5-[(E)-2-methylsulfanyl-2-(toluene-4-sulfonyl)-vinyl]-benzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

methylthiomethyl p-tolyl sulfone (59662-65-6) + 3,4,5-trimethoxy-benzaldehyde (86-81-7) → 1,2,3-Trimethoxy-5-[(E)-2-methylsulfanyl-2-(toluene-4-sulfonyl)-vinyl]-benzene (107951-75-7)

Guidance literature:

With potassium carbonate; In isopropyl alcohol; Heating;

DOI:10.1246/cl.1986.1597

Reference yield: 95.0%

1,2,3-Trimethoxy-5-[(E)-2-methylsulfanyl-2-(toluene-4-sulfonyl)-vinyl]-benzene (107951-75-7) → 1,2,3-Trimethoxy-5-[2-methylsulfanyl-2-(toluene-4-sulfonyl)-ethyl]-benzene (107951-78-0)

Guidance literature:

With sodium tetrahydroborate; In ethanol; for 6h; Ambient temperature;

DOI:10.1246/cl.1986.1597

Reference yield:

1,2,3-Trimethoxy-5-[(E)-2-methylsulfanyl-2-(toluene-4-sulfonyl)-vinyl]-benzene (107951-75-7) → (3,4,5-trimethoxyphenyl)acetone (16603-18-2)

Guidance literature:

Multi-step reaction with 3 steps

1: 95 percent / NaBH₄ / ethanol / 6 h / Ambient temperature

2: NaH / dimethylformamide / 1.) 0 deg C, 6 h; 2.) RT, 18 h

3: cc. HCl / methanol / Heating

With hydrogenchloride; sodium tetrahydroborate; sodium hydride; In methanol; ethanol; N,N-dimethyl-formamide;

DOI:10.1246/cl.1986.1597

upstream raw materials:

methylthiomethyl p-tolyl sulfone

3,4,5-trimethoxy-benzaldehyde

Downstream raw materials:

1,2,3-Trimethoxy-5-[2-methylsulfanyl-2-(toluene-4-sulfonyl)-ethyl]-benzene

(3,4,5-trimethoxyphenyl)acetone

1,2,3-Trimethoxy-5-[2-methylsulfanyl-2-(toluene-4-sulfonyl)-propyl]-benzene