chloro[2,6-bis[(diethylamino)methyl]phenyl]germylene

Base Information

• Chemical Name: chloro[2,6-bis[(diethylamino)methyl]phenyl]germylene
• CAS No.: 444718-17-6
• Molecular Formula: C₁₆H₂₇ClGeN₂
• Molecular Weight: 355.447
• Mol file: 444718-17-6.mol

Synonyms:chloro[2,6-bis[(diethylamino)methyl]phenyl]germylene

Chemical Property of chloro[2,6-bis[(diethylamino)methyl]phenyl]germylene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of chloro[2,6-bis[(diethylamino)methyl]phenyl]germylene

There total 1 articles about chloro[2,6-bis[(diethylamino)methyl]phenyl]germylene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

1-lithio-2,6-bis[(diethylamino)methyl]benzene + germanium(II) chloride dioxane → chloro[2,6-bis[(diethylamino)methyl]phenyl]germylene (444718-17-6)

Guidance literature:

In tetrahydrofuran; byproducts: LiCl, C4H8O2; (Ar), mixed dropwise in THF at -78°C, warmed to room temp., stirred for 30 min; evapd.(vac.), treated with pentane, filtered, concd. (vac.), crystd. from pentane soln. at room temp. within several hours; elem. anal.;

DOI:10.1016/S0277-5387(02)01279-2

Reference yield: 83.0%

chloro[2,6-bis[(diethylamino)methyl]phenyl]germylene (444718-17-6) + sodium iodide (7681-82-5,24359-64-6,41927-88-2,115813-40-6) → C16H27GeIN2

Guidance literature:

at 20 ℃; for 18h;

DOI:10.1002/anie.202104643

Reference yield: 41.0%

chloro[2,6-bis[(diethylamino)methyl]phenyl]germylene (444718-17-6) + lithium hexamethyldisilazane (4039-32-1) → [2,6-bis((diethylamino)methyl)phenyl]GeN(SiMe3)2

Guidance literature:

In tetrahydrofuran; diethyl ether; under N2 atm. soln. LiN(SiMe3)2 in Et2O was added to soln. ArGeCl in THFat -78°C, allowed to warm to room temp. and stirred for 3 h; volatiles were removed, residue was extd. with pentane, filtered, and kept at -20°C; elem. anal.;

DOI:10.1021/om020187y

Downstream raw materials:

[2,6-bis((diethylamino)methyl)phenyl]GeOC₆H₂-2,4,6-Me₃