ethyl 2-(1-(4-(benzyloxy)-2-hydroxyphenyl)ethylidene)hydrazine carboxylate

Base Information

• Chemical Name: ethyl 2-(1-(4-(benzyloxy)-2-hydroxyphenyl)ethylidene)hydrazine carboxylate
• CAS No.: 1384938-78-6
• Molecular Formula: C₁₈H₂₀N₂O₄
• Molecular Weight: 328.368
• Mol file: 1384938-78-6.mol

Synonyms:ethyl 2-(1-(4-(benzyloxy)-2-hydroxyphenyl)ethylidene)hydrazine carboxylate

Chemical Property of ethyl 2-(1-(4-(benzyloxy)-2-hydroxyphenyl)ethylidene)hydrazine carboxylate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of ethyl 2-(1-(4-(benzyloxy)-2-hydroxyphenyl)ethylidene)hydrazine carboxylate

There total 2 articles about ethyl 2-(1-(4-(benzyloxy)-2-hydroxyphenyl)ethylidene)hydrazine carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2',4'-dihydroxy-4-acetophenone (89-84-9) → ethyl 2-(1-(4-(benzyloxy)-2-hydroxyphenyl)ethylidene)hydrazine carboxylate (1384938-78-6)

Guidance literature:

Multi-step reaction with 2 steps

1: potassium carbonate / acetone / 5 h / 48 °C

2: propan-1-ol / 24 h / 100 °C

With potassium carbonate; In propan-1-ol; acetone;

Reference yield:

benzyl bromide (100-39-0) → ethyl 2-(1-(4-(benzyloxy)-2-hydroxyphenyl)ethylidene)hydrazine carboxylate (1384938-78-6)

Guidance literature:

Multi-step reaction with 2 steps

1: potassium carbonate / acetone / 5 h / 48 °C

2: propan-1-ol / 24 h / 100 °C

With potassium carbonate; In propan-1-ol; acetone;

Reference yield: 63.0%

ethyl 2-(1-(4-(benzyloxy)-2-hydroxyphenyl)ethylidene)hydrazine carboxylate (1384938-78-6) → 4-(4-benzyloxy-2-hydroxyphenyl)-1,2,3-thiadiazole (1384938-86-6)

Guidance literature:

With thionyl chloride; In chloroform; at 60 ℃; for 1h;

DOI:10.1134/S1070428012050168

upstream raw materials:

2',4'-dihydroxy-4-acetophenone

benzyl bromide

Downstream raw materials:

6-benzyloxy-2-benzylsulfanylbenzo[b]furan

4-(4-benzyloxy-2-hydroxyphenyl)-1,2,3-thiadiazole