ethyl 4-((2-(1H-pyrazol-1-yl)benzyl)amino)-8-isopropyl-pyrazolo[1,5-a][1,3,5]triazine-2-carbimidate hydrochloride

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Chemical Name:ethyl 4-((2-(1H-pyrazol-1-yl)benzyl)amino)-8-isopropyl-pyrazolo[1,5-a][1,3,5]triazine-2-carbimidate hydrochloride
CAS No.:1453836-35-5
Molecular Formula:C₂₁H₂₄N₈O*ClH
Molecular Weight:440.936
Hs Code.:

Synonyms:ethyl 4-((2-(1H-pyrazol-1-yl)benzyl)amino)-8-isopropyl-pyrazolo[1,5-a][1,3,5]triazine-2-carbimidate hydrochloride

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Chemical Property of ethyl 4-((2-(1H-pyrazol-1-yl)benzyl)amino)-8-isopropyl-pyrazolo[1,5-a][1,3,5]triazine-2-carbimidate hydrochloride

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Technology Process of ethyl 4-((2-(1H-pyrazol-1-yl)benzyl)amino)-8-isopropyl-pyrazolo[1,5-a][1,3,5]triazine-2-carbimidate hydrochloride

There total 8 articles about ethyl 4-((2-(1H-pyrazol-1-yl)benzyl)amino)-8-isopropyl-pyrazolo[1,5-a][1,3,5]triazine-2-carbimidate hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 64-17-5
ethanol

: 1453836-25-3
C₁₉H₁₈N₈

: 1453836-35-5
ethyl 4-((2-(1H-pyrazol-1-yl)benzyl)amino)-8-isopropyl-pyrazolo[1,5-a][1,3,5]triazine-2-carbimidate hydrochloride

Guidance literature:: With hydrogenchloride; at 60 ℃;

Reference yield:

: 1453186-96-3
4-chloro-2-(methylsulfanyl)-8-(propan-2-yl)pyrazolo[1,5-a][1,3,5]triazine

: 1453836-35-5
ethyl 4-((2-(1H-pyrazol-1-yl)benzyl)amino)-8-isopropyl-pyrazolo[1,5-a][1,3,5]triazine-2-carbimidate hydrochloride

Guidance literature:: Multi-step reaction with 4 steps

1: N-ethyl-N,N-diisopropylamine / acetonitrile / 50 °C

2: 3-chloro-benzenecarboperoxoic acid / dichloromethane / 4 h / 30 °C

3: 1-methyl-pyrrolidin-2-one / 4 h / 80 °C

4: hydrogenchloride / 60 °C

With hydrogenchloride; N-ethyl-N,N-diisopropylamine; 3-chloro-benzenecarboperoxoic acid; In 1-methyl-pyrrolidin-2-one; dichloromethane; acetonitrile;

Reference yield:

: 1453186-94-1
8-isopropyl-2-thioxo-2,3-dihydropyrazolo[1,5-a][1,3,5]triazin-4(1H)-one

: 1453836-35-5
ethyl 4-((2-(1H-pyrazol-1-yl)benzyl)amino)-8-isopropyl-pyrazolo[1,5-a][1,3,5]triazine-2-carbimidate hydrochloride

Guidance literature:: Multi-step reaction with 6 steps

1: sodium hydroxide / ethanol; water / Cooling with ice

2: N,N-diethylaniline; trichlorophosphate / 3 h / 90 °C

3: N-ethyl-N,N-diisopropylamine / acetonitrile / 50 °C

4: 3-chloro-benzenecarboperoxoic acid / dichloromethane / 4 h / 30 °C

5: 1-methyl-pyrrolidin-2-one / 4 h / 80 °C

6: hydrogenchloride / 60 °C

With hydrogenchloride; N-ethyl-N,N-diisopropylamine; 3-chloro-benzenecarboperoxoic acid; N,N-diethylaniline; sodium hydroxide; trichlorophosphate; In 1-methyl-pyrrolidin-2-one; ethanol; dichloromethane; water; acetonitrile;