2-methyl-propane-2-sulfinic acid 8-(4-fluoro-phenyl)-1,4-dioxa-spiro[4.5]dec-8-ylmethyleneamide

Base Information

Chemical Name:2-methyl-propane-2-sulfinic acid 8-(4-fluoro-phenyl)-1,4-dioxa-spiro[4.5]dec-8-ylmethyleneamide
CAS No.:1202008-69-2
Molecular Formula:C₁₉H₂₆FNO₃S
Molecular Weight:367.485
Hs Code.:

Synonyms:2-methyl-propane-2-sulfinic acid 8-(4-fluoro-phenyl)-1,4-dioxa-spiro[4.5]dec-8-ylmethyleneamide

Suppliers and Price of 2-methyl-propane-2-sulfinic acid 8-(4-fluoro-phenyl)-1,4-dioxa-spiro[4.5]dec-8-ylmethyleneamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 2-methyl-propane-2-sulfinic acid 8-(4-fluoro-phenyl)-1,4-dioxa-spiro[4.5]dec-8-ylmethyleneamide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 2-methyl-propane-2-sulfinic acid 8-(4-fluoro-phenyl)-1,4-dioxa-spiro[4.5]dec-8-ylmethyleneamide

There total 3 articles about 2-methyl-propane-2-sulfinic acid 8-(4-fluoro-phenyl)-1,4-dioxa-spiro[4.5]dec-8-ylmethyleneamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1006685-87-5
8-(4-fluoro-phenyl)-1,4-dioxa-spiro[4.5]decane-8-carbaldehyde

: 146374-27-8
S-tert-butylsulfinimide

: 1202008-69-2
2-methyl-propane-2-sulfinic acid 8-(4-fluoro-phenyl)-1,4-dioxa-spiro[4.5]dec-8-ylmethyleneamide

Guidance literature:: With titanium(IV) tetraethanolate; In tetrahydrofuran; at 20 ℃; for 19h; Reflux;

Reference yield:

: 459-22-3
4-fluorophenylacetonitrile

: 1202008-69-2
2-methyl-propane-2-sulfinic acid 8-(4-fluoro-phenyl)-1,4-dioxa-spiro[4.5]dec-8-ylmethyleneamide

Guidance literature:: Multi-step reaction with 5 steps

1: sodium methylate / tetrahydrofuran; methanol / 20 - 50 °C

2: hydrogenchloride / ethanol; water / 40 h / Reflux

3: toluene-4-sulfonic acid / toluene / 6 h / Heating

4: diisobutylaluminium hydride / tetrahydrofuran; toluene / -78 - 0 °C

5: titanium(IV) tetraethanolate / tetrahydrofuran / 19 h / 20 °C / Reflux

With hydrogenchloride; titanium(IV) tetraethanolate; sodium methylate; diisobutylaluminium hydride; toluene-4-sulfonic acid; In tetrahydrofuran; methanol; ethanol; water; toluene;

Reference yield:

: 56326-95-5
methyl 5-cyano-5-(4-fluorophenyl)-2-oxocyclohexanecarboxylate

: 1202008-69-2
2-methyl-propane-2-sulfinic acid 8-(4-fluoro-phenyl)-1,4-dioxa-spiro[4.5]dec-8-ylmethyleneamide

Guidance literature:: Multi-step reaction with 4 steps

1: hydrogenchloride / ethanol; water / 40 h / Reflux

2: toluene-4-sulfonic acid / toluene / 6 h / Heating

3: diisobutylaluminium hydride / tetrahydrofuran; toluene / -78 - 0 °C

4: titanium(IV) tetraethanolate / tetrahydrofuran / 19 h / 20 °C / Reflux

With hydrogenchloride; titanium(IV) tetraethanolate; diisobutylaluminium hydride; toluene-4-sulfonic acid; In tetrahydrofuran; ethanol; water; toluene;