56326-95-5

Basic information

• Product Name: Cyclohexanecarboxylic acid, 5-cyano-5-(4-fluorophenyl)-2-oxo-, methyl ester
• CAS NO: 56326-95-5
• Molecular Formula: C15H14FNO3
• Molecular Weight: 275.279
• Mol File: 56326-95-5.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: Cyclohexanecarboxylic acid, 5-cyano-5-(4-fluorophenyl)-2-oxo-, methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Cyclohexanecarboxylic acid, 5-cyano-5-(4-fluorophenyl)-2-oxo-, methyl ester(56326-95-5)
• EPA Substance Registry System: Cyclohexanecarboxylic acid, 5-cyano-5-(4-fluorophenyl)-2-oxo-, methyl ester(56326-95-5)

Safety Data

• Hazardous Substances Data: 56326-95-5(Hazardous Substances Data)

Upstream product

• 459-22-3 4-fluorophenylacetonitrile 
• 292638-85-8 acrylic acid methyl ester 
• 56326-92-2 Dimethyl diester of 4-cyano-4-(p-fluorophenyl)pimelic acid 

Downstream Products

• 1202176-63-3 cis-2-methyl-propane-2-sulfinic acid {2-benzenesulfonyl-1-[4-(tert-butyl-dimethyl-silanyloxy)-1-(4-fluoro-phenyl)-cyclohexyl]-2-fluoro-ethyl}-amide 
• 1202007-07-5 trans-4-(1-amino-butyl)-4-(4-fluoro-phenyl)-cyclohexanol hydrochloride 
• 1202007-12-2 cis-1-[4-(7-chloro-1-methoxy-isoquinolin-6-yloxy)-1-(4-fluoro-phenyl)-cyclohexyl]-propylamine 
• 1202008-66-9 cis-2-methyl-propane-2-sulfinic acid {1-[4-(tert-butyl-dimethyl-silanyloxy)-1-(4-fluoro-phenyl)-cyclohexyl]-2-fluoro-ethyl}-amide 
• 1202008-72-7 C₂₁H₃₂FNO₄S 
• 1202008-71-6 2-methyl-propane-2-sulfinic acid {1-[8-(4-fluoro-phenyl)-1,4-dioxa-spiro[4.5]dec-8-yl]-3-methoxy-propyl}-amide 
• 1202007-03-1 {1-[8-(4-fluoro-phenyl)-1,4-dioxa-spiro[4.5]dec-8-yl]-butyl}-carbamic acid tert-butyl ester 
• 1202008-65-8 cis-2-methyl-propane-2-sulfinic acid 1-[4-(tert-butyl-dimethyl-silanyloxy)-1-(4-fluoro-phenyl)-cyclohexyl]-methylideneamide 
• 1202008-51-2 C₂₀H₃₃FO₄SSi 
• 1202007-05-3 trans-{1-[1-(4-fluoro-phenyl)-4-hydroxy-cyclohexyl]-butyl}-carbamic acid tert-butyl ester 
• 1202008-70-5 2-methyl-propane-2-sulfinic acid {1-[8-(4-fluoro-phenyl)-1,4-dioxa-spiro[4.5]dec-8-yl]-allyl}-amide 
• 1202008-50-1 cis-[4-(tert-butyl-dimethyl-silanyloxy)-1-(4-fluoro-phenyl)-cyclohexyl]-acetonitrile 
• 1202007-04-2 {1-[1-(4-fluoro-phenyl)-4-oxo-cyclohexyl]-butyl}-carbamic acid tert-butyl ester 
• 1202007-21-3 C₁₉H₃₁FO₂Si 

Relevant articles and documents

Synthesis and optimization of novel 4,4-disubstituted cyclohexylbenzamide derivatives as potent 11β-HSD1 inhibitors

The synthesis and SAR of a series of 4,4-disubstituted cyclohexylbenzamide inhibitors of 11β-HSD1 are described. Optimization rapidly led to potent, highly selective, and orally bioavailable inhibitors demonstrating efficacy in both rat and non-human primate ex vivo pharmacodynamic models.

CYCLOALKYLAMINE SUBSTITUTED ISOQUINOLINE AND ISOQUINOLINONE DERIVATIVES

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Benzamide derivatives and uses related thereto

Benzamide derivatives of formula I are described and have therapeutic utility, particularly in the treatment of diabetes, obesity and related conditions and disorders: wherein R1, R2, R3, R4, R5, R6, R7, R8, and n are as defined herein.